Journal ArticleDOI
Epidemiology of diabetes mellitus in the elderly: The Framingham study
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TLDR
Factors potentially associated with adult-onset diabetes mellitus in the elderly were reviewed, using the Framingham Heart Study data and other population data, finding that Hypertension and coexistent vascular disease were particularly common in elderly diabetic patients.About:
This article is published in The American Journal of Medicine.The article was published on 1986-05-16. It has received 239 citations till now. The article focuses on the topics: Framingham Heart Study & Diabetes mellitus.read more
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Lipid-induced insulin resistance: unravelling the mechanism
TL;DR: This unifying hypothesis accounts for the mechanism of insulin resistance in obesity, type 2 diabetes, lipodystrophy, and ageing; and the insulin-sensitising effects of thiazolidinediones.
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Increased Risk of Type 2 Diabetes in Alzheimer Disease
Juliette Janson,Thomas Laedtke,Joseph E. Parisi,Peter C. O'Brien,Ronald C. Petersen,Peter C. Butler +5 more
TL;DR: The hypothesis that patients with Alzheimer disease are more vulnerable to type 2 diabetes and the possibility of linkage between the processes responsible for loss of brain cells and beta-cells in these diseases are supported.
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Weight as a risk factor for clinical diabetes in women
Graham A. Colditz,Walter C. Willett,Walter C. Willett,Meir J. Stampfer,Meir J. Stampfer,JoAnn E. Manson,JoAnn E. Manson,Charles H. Hennekens,Charles H. Hennekens,Ronald A. Arky,Frank E. Speizer +10 more
TL;DR: Weight gain after age 18 was a major determinant of risk and the relation between body mass index and risk of diabetes is continuous, indicating that, at even average weight, women are at increased risk of clinical non-insulin-dependent diabetes.
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Prospective study of cigarette smoking, alcohol use, and the risk of diabetes in men.
TL;DR: Cigarette smoking may be an independent, modifiable risk factor for non-insulin dependent diabetes mellitus and moderate alcohol consumption among healthy people may be associated with increased insulin sensitivity and a reduced risk of diabetes.
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Parental transmission of type 2 diabetes: the Framingham Offspring Study.
TL;DR: Risk ratios for offspring type 2 diabetes are consistent with a simple additive risk model, where risk when both parents are affected equals the sum of risk when either parent is affected.
References
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Relation of Body Fat Distribution to Metabolic Complications of Obesity
TL;DR: In women, the sites of fat predominance offer an important prognostic marker for glucose intolerance, hyperinsulinemia, and hypertriglyceridemia, may be related to the disparate morphology and metabolic behavior of fat cells associated with different body fat distributions.
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Estimation of the probability of an event as a function of several independent variables
TL;DR: A recursive approach based on Kalman's work in linear dynamic filtering and prediction is applied, derivable also from the work of Swerling (1959), which provides an example of many other possible uses of recursive techniques in nonlinear estimation and in related areas.
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Age of Onset and Type of Diabetes
Markku Laakso,Kalevi Pyörälä +1 more
TL;DR: Nearly all patients diagnosed before the age of 19 had IDDM, but a large proportion (37%) of all diagnoses of IDDM were made after that age, and the proportion increased rapidly in older age groups.