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Estudio de la actividad antibacteriana y la toxicidad en gambas en salmuera de dos especies de Polygonum Assessment of anti-bacterial activity and brine shrimp toxicity of two Polygonum species

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TLDR
All extracts and fractions displayed considerable general toxicity towards brine shrimps, and exhibited low to moderate levels of anti-bacterial activity against most of the test strains.
Abstract
The extracts of the aerial parts of Polygonum barbatum var. barbata and Polygonum stagninum (Family: Polygonaceae) were assessed for anti-bacterial activity against a number of bacterial strains using the disc diffusion assay, and brine shrimp toxicity using the brine shrimp lethality assay. All extracts/fractions, except the MeOH extract/fraction, exhibited low to moderate levels of anti-bacterial activity against most of the test strains (zone of inhibition = 7-21 mm). All extracts and fractions displayed considerable general toxicity towards brine shrimps. The LD 50 values of the test extracts/fractions were within the range of 2.19 to 114.81 mg/mL, whereas that of the positive control (vincristine sulphate) was 0.61 mg/mL.

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In vivo antipyretic, antiemetic, in vitro membrane stabilization, antimicrobial, and cytotoxic activities of different extracts from Spilanthes paniculata leaves

TL;DR: The results showed that the n-hexane extract has better effects than the other in all trials, and can be said that the leaves of S. paniculata possess remarkable pharmacological effects, and justify its folkloric use as antimicrobial, antipyretic, anti-inflammatory, and antiemetic agent.
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Pharmacological effects of the phytochemicals of Anethum sowa L. root extracts

TL;DR: Results showed that the Anethum sowa root extracts are the important source of the antioxidant, antimicrobial and cytotoxic agent and it is necessary to isolate and characterize of different phytoconstituents for pharmaceutical drug lead molecules.
Journal ArticleDOI

Evaluation of antioxidant, anti-hemolytic, cytotoxic effects and anti-bacterial activity of selected mangrove plants ( Bruguiera gymnorrhiza and Heritiera littoralis ) in Bangladesh

TL;DR: In this article, methanol extracts of Bruguiera gymnorrhiza and Heritiera littoralis were investigated in order to determine their medicinal activities, including antioxidant, anti-hemolytic, cytotoxic and anti-bacterial activities.
References
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Brine shrimp: a convenient general bioassay for active plant constituents.

TL;DR: Screening results with seed extracts of 41 species of Euphorbiaceae were compared with 9KB and 9PS cytotoxicities and the method is rapid, reliable, inexpensive, and convenient as an in-house general bioassay tool.

A convenient general bioassay for active plant constituents

TL;DR: In this article, a simple bioassay for natural product research using brine shrimp (Artemia salina leach) is proposed, which determines LC (50) values in microg/ml of active compounds and extracts in the brine medium.
Journal ArticleDOI

Probit Analysis (3rd ed).

J. A. Lewis, +1 more
- 01 Jan 1972 - 
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