Journal ArticleDOI
Evidence for the existence of α- and β-adrenoceptors on cultured glial cells—an electrophysiological study
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TLDR
The present results, together with those of biochemical and autoradiographic binding studies, suggest that α- and β-adrenoceptors occur on glial cells and that the glial depolarized is mediated by α-receptors, whereas the hyperpolarization is due to activation of β-receptionors.About:
This article is published in Neuroscience.The article was published on 1982-11-01. It has received 91 citations till now. The article focuses on the topics: Depolarization & Hyperpolarization (biology).read more
Citations
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Journal ArticleDOI
Role of glial cells in the regulation of the brain ion microenvironment
Journal ArticleDOI
Functional receptors for neurotransmitters on astroglial cells
S. Murphy,B. Pearce +1 more
TL;DR: La question posee est de savoir si les astrocytes sont des sites «accepteurs» ou s'ils sont de veritables sites recepteurs fonctionnellement couples au metabolisme intercellulaire induisant lors d'une activation une reponse cellulaire biologique significative.
Journal ArticleDOI
Excitatory amino acids directly depolarize rat brain astrocytes in primary culture
C. L. Bowman,H. K. Kimelberg +1 more
TL;DR: The membrane potential of astrocytes can no longer be thought of as being responsive only to K+ and that the electrophysiological effects of excitatory amino acids in situ may not be exclusively a neuronal property.
Journal ArticleDOI
Basolateral Amygdala Noradrenergic Influences on Memory Storage Are Mediated by an Interaction between β- and α1-Adrenoceptors
TL;DR: These findings are consistent with the view that α1-adrenoceptors affect memory storage by modulating β- adrenoceptor activation in the BLA, and are also consistent with those of pharmacological studies indicating that β-adreceptors modulate memory storageBy a direct coupling to adenylate cyclase, whereasα1-receptor act indirectly by influencing the β-adsenosine-mediated influence on cAMP formation.
Journal ArticleDOI
The role of astrocytes in hepatic encephalopathy.
TL;DR: These studies indicate that profound changes occur in astrocytes following exposure to ammonia and other putative toxins, and it is proposed that toxins and factors involved in the precipitation of HE do so by affecting astroglial properties.
References
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Journal ArticleDOI
Cyclic adenosine monophosphate and norepinephrine: effects on transmembrane properties of cerebellar Purkinje cells.
TL;DR: Results show that cyclic nucleotides mimic the unique effects of norepinephrine on the bioelectric properties of neuronal membranes.
Journal ArticleDOI
Neurotransmitter receptor binding in bovine cerebral microvessels
Stephen J. Peroutka,Michael A. Moskowitz,Michael A. Moskowitz,John F. Reinhard,Solomon H. Snyder +4 more
TL;DR: Purified preparations of microvessels from bovine cerebral cortex contain substantial levels of alpha-adrenergic, beta-adRenergic, and histamine 1 receptor binding sites but only negligible serotonin, muscarinic cholinergic, opiate, and benzodiazepine receptor binding.
Book ChapterDOI
Action and uptake of neurotransmitters in CNS tissue culture.
L. Hösli,Elisabeth Hösli +1 more
Journal ArticleDOI
The action of norepinephrine in the rat hippocampus: Intracellular studies in the slice preparation
TL;DR: It is proposed that norepinephrine activates two mechanisms; one involves activation of Cl- conductance and the other activation of a Na+-K+ pump, which might be mediated by cAMP.
Journal ArticleDOI
THE PHARMACOLOGY OF ADRENERGIC NEURONAL RESPONSES IN THE CEREBRAL CORTEX: EVIDENCE FOR EXCITATORY α‐ AND INHIBITORY β‐RECEPTORS
TL;DR: It is concluded that responses of cortical neurones to adrenoceptor agonists are mediated by both α‐ and β‐receptors and give rise to opposite effects: the α‐receptor being excitatory and the β‐ receptors being inhibitory; and responses of many neurones reflect the presence of both types of receptor.
Related Papers (5)
Alpah-adrenergic receptor modulation of beta-adrenergic, adenosine and prostaglandin E1 increased adenosine 3':5'-cyclic monophosphate levels in primary cultures of glia.
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Excitatory amino acids directly depolarize rat brain astrocytes in primary culture
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