Journal ArticleDOI
Extending the scope of enantiomer separation on diluted methylated β‐cyclodextrin derivatives by high‐resolution gas chromatography
TLDR
In this paper, high-resolution open-tubular columns coated with solutions of heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin (phase I) or heptonakis (2,6,di-O-,methyl-3,O-trifluoroacetyl)-β -cyclodextrin (Phase II) in moderately polar polysiloxanes such as OV-1701 (5% cyanopropyl/7% phenyl/88% methylpolysiloxane) and OVAbstract:
High-resolution open-tubular columns coated with solutions of heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin (Phase I) or heptakis(2,6-di-O-methyl-3-O-trifluoroacetyl)-β-cyclodextrin (Phase II) in moderately polar polysiloxanes such as OV-1701 (5% cyanopropyl/7% phenyl/88% methylpolysiloxane) and OV-225 (25% cyanopropyl/50% phenyl/25% methylpolysiloxane) are used for the gas chromatographic enantiomer separation of volatiles belonging to different classes of compounds. No derivatization procedures are necessary for most of the resolved chiral molecules. The chiral stationary phases can be operated between 25 and 190°C for extended periods of time. The enantiomer separation of saturated, unfunctionalized hydrocarbons clearly demonstrates the importance of molecular inclusion in chiral recognition using cyclodextrins for this class of compounds. The different, and in some cases complementary, selectivity of the Phases I and II is demonstrated.read more
Citations
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Journal ArticleDOI
Cyclodextrins as chiral stationary phases in capillary gas chromatography. Part V: Octakis(3‐O‐butyryl‐2,6‐di‐O‐pentyl)‐γ‐cyclodextrin
TL;DR: γ-Cyclodextrin with 3-Obutyryl and 2,6-di-O-pentyl residues is a very versatile chiral stationary phase for enantiomer separation as discussed by the authors.
Journal ArticleDOI
Cyclodextrine als Bausteine supramolekularer Strukturen und Funktionseinheiten
TL;DR: Cyclodextrine werden gerne als Bausteine eingesetzt, da sie sich gezielt sowohl kovalent, als auch nichtkovalent verknupfen lassen.
Journal ArticleDOI
Enantiomer separation by gas chromatography on chiral stationary phases
TL;DR: The analytical separation of enantiomers by capillary gas chromatography on chiral stationary phases (CSPs) is reviewed in this article, where three principal CSPs tailored for hydrogen bonding, coordination and inclusion are currently employed.
Journal ArticleDOI
Essential oils and volatiles: sample preparation and analysis. A review
TL;DR: A short overview of the state of the art in essential oil analysis can be found in this article, where several aspects of the analysis of essential oils and volatile fraction of vegetable matrices are discussed.
Journal ArticleDOI
Enantioselective determination of chiral organochlorine compounds in biota by gas chromatography on modified cyclodextrins
Walter Vetter,Volker Schurig +1 more
TL;DR: Approaches to the gas chromatographic enantiomer separation of chiral organchlorines (alpha-hexachlorocyclohexane, cis- and trans-chlordane, heptachlor, heptonachlorepoxide, oxychlordanes, o,p'-DDT, compounds of technical toxaphene and stable atropisomeric polychlorinated biphenyls) are reviewed.
References
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Journal ArticleDOI
Separation of enantiomers on diluted permethylated β-cyclodextrin by high-resolution gas chromatography
Volker Schurig,H.-P. Nowotny +1 more
TL;DR: In this article, a number of volatile racemic solutes belonging to different classes of compounds have been resolved on permethylated β-cyclodextrin in OV-1701 on high-resolution glass open-tubular columns.
Journal ArticleDOI
Cyclodextrin chemistry. Selective modification of all primary hydroxyl groups of α- and β-cyclodextrins
TL;DR: In this article, two efficient methods for the selective modification of all six primary hydroxyl groups of α-cyclodextrin (α-CD, 11) were described, one using an indirect strategy, which involves protection of all 18 hydrastic functions as benzoate esters, followed by selective deprotection of the six primary alcohol groups.
Journal ArticleDOI
Extending the scope of enantiomer resolution by complexation gas chromatography
Volker Schurig,Waldemar Buerkle +1 more
Journal ArticleDOI
Conformation of O-methylated amylose and cyclodextrins☆
TL;DR: In this paper, the conformation of the glucopyranose units of O-methylated amylose, cyclodextrins and of model O -methylated glucoses and di-glucoses was investigated by PMR and IR spectroscopy.
Journal ArticleDOI
Deactivation of glass capillary columns by silylation. Part 1: Principles and basic technique
TL;DR: In this paper, a deactivation procedure based on a published method using hexamethyldisilazane in the gas phase is described, which produces truly neutral columns which allow simultaneous analysis of moderately strong free acids and bases.
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Separation of enantiomers on diluted permethylated β-cyclodextrin by high-resolution gas chromatography
Volker Schurig,H.-P. Nowotny +1 more