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Fatty acid composition of single brain structures following different alpha linolenate dietary supplementations.

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TLDR
A different sensitivity to the diet of the different structures examined and a strong decrease in the proportions of the total (n-6 + n-3) polyunsaturated fatty acids in all the structures examined is demonstrated.
Abstract
Weanling female rats randomly divided into three groups were fed a basal alipidic diet added with 10% (w/w) corn oil, soybean oil or linseed oil. After thirty and ninety days of dietary treatment the rats were killed and the fatty acid composition of brain, optic nerve and visual cortex was determined. The results demonstrate a different sensitivity to the diet of the different structures examined and, for the linseed oil treated rats, a strong decrease in the proportions of the total (n-6 + n-3) polyunsaturated fatty acids in all the structures examined.

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reversibility of n-3 fatty acid deficiency and turnover of docosahexaenoic acid in the brain, erythrocytes, and plasma of rhesus monkeys'

TL;DR: Connor et al. as mentioned in this paper showed that the brain fat acid composition of rhesus monkeys changed after eating fish oil for up to 129 weeks and that the changes of brain fatty acid composition began as early as 1 week after fish oil feeding and stabilized at 12 weeks.
Journal ArticleDOI

Dietary effects on brain fatty acid composition: the reversibility of n-3 fatty acid deficiency and turnover of docosahexaenoic acid in the brain, erythrocytes, and plasma of rhesus monkeys.

TL;DR: In this paper, the results of serial biopsy samples of the cerebral cortex indicated that the changes of brain fatty acid composition began as early as 1 week after fish oil feeding and stabilized at 12 weeks.
Journal ArticleDOI

Neural 22‐Carbon Fatty Acids in the Weanling Rat Respond Rapidly and Specifically to a Range of Dietary Linoleic to of‐Linolenic Fatty Acid Ratios

TL;DR: It is shown that the 18:2n6/18:3n3 ratio of diets high in fat and adequate in EFA, both typical of diets in developed countries, can substantially and relatively quickly affect the 22‐carbon fatty acids in the brain, even after the rapid accumulation of these fatty acids during neural growth has ceased.

Dietary N-3 Fatty Acid Deficiency and Its Reversibility

TL;DR: It now appears that both n-6 and n-3 fatty acids are essential for health.
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