Journal ArticleDOI
Final Version of the American Joint Committee on Cancer Staging System for Cutaneous Melanoma
Charles M. Balch,Antonio C. Buzaid,Seng Jaw Soong,Michael B. Atkins,Natale Cascinelli,Daniel G. Coit,Irvin D. Fleming,Jeffrey E. Gershenwald,Alan Houghton,John M. Kirkwood,Kelly M. McMasters,Martin F. Mihm,Donald L. Morton,Douglas S. Reintgen,M. I. Ross,Arthur J. Sober,John A. Thompson,John F. Thompson +17 more
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TLDR
This revision of the staging system for cutaneous melanoma will become official with publication of the sixth edition of the AJCC Cancer Staging Manual in the year 2002.Abstract:
PURPOSE: To revise the staging system for cutaneous melanoma under the auspices of the American Joint Committee on Cancer (AJCC). MATERIALS AND METHODS: The prognostic factors analysis described in the companion publication (this issue), as well as evidence from the published literature, was used to assemble the tumor-node-metastasis criteria and stage grouping for the melanoma staging system. RESULTS: Major changes include (1) melanoma thickness and ulceration but not level of invasion to be used in the T category (except for T1 melanomas); (2) the number of metastatic lymph nodes rather than their gross dimensions and the delineation of clinically occult (ie, microscopic) versus clinically apparent (ie, macroscopic) nodal metastases to be used in the N category; (3) the site of distant metastases and the presence of elevated serum lactic dehydrogenase to be used in the M category; (4) an upstaging of all patients with stage I, II, and III disease when a primary melanoma is ulcerated; (5) a merging of sa...read more
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Journal ArticleDOI
Final Version of 2009 AJCC Melanoma Staging and Classification
Charles M. Balch,Jeffrey E. Gershenwald,Seng-Jaw Soong,John F. Thompson,Michael B. Atkins,David R. Byrd,Antonio C. Buzaid,Alistair J. Cochran,Daniel G. Coit,Shouluan Ding,Alexander M.M. Eggermont,Keith T. Flaherty,Phyllis A. Gimotty,John M. Kirkwood,Kelly M. McMasters,Martin C. Mihm,Donald L. Morton,Merrick I. Ross,Arthur J. Sober,Vernon K. Sondak +19 more
TL;DR: Revised melanoma staging system has been made that reflect the improved understanding of this disease and will be formally incorporated into the seventh edition of the AJCC Cancer Staging Manual and implemented by early 2010.
Journal ArticleDOI
Prognostic Factors Analysis of 17,600 Melanoma Patients: Validation of the American Joint Committee on Cancer Melanoma Staging System
Charles M. Balch,Seng Jaw Soong,Jeffrey E. Gershenwald,John F. Thompson,Douglas S. Reintgen,Natale Cascinelli,Marshall M. Urist,Kelly M. McMasters,M. I. Ross,John M. Kirkwood,Michael B. Atkins,John A. Thompson,Daniel G. Coit,David R. Byrd,Renee A. Desmond,Yuting Zhang,Ping-Yu Liu,Gary H. Lyman,Aberto Morabito +18 more
TL;DR: The proposed tumor-node-metastases categories and stage groupings for cutaneous melanoma patients were validated and incorporated into the AJCC melanoma staging as described in the companion publication.
Journal ArticleDOI
Sentinel-node biopsy or nodal observation in melanoma
Donald L. Morton,John F. Thompson,Alistair J. Cochran,Nicola Mozzillo,Robert Elashoff,Richard Essner,Omgo E. Nieweg,Daniel F. Roses,Harald J Hoekstra,Constantine P. Karakousis,Douglas S. Reintgen,Brendon J. Coventry,Edwin C. Glass,He-Jing Wang +13 more
TL;DR: The staging of intermediate-thickness primary melanomas according to the results of sentinel-node biopsy provides important prognostic information and identifies patients with nodal metastases whose survival can be prolonged by immediate lymphadenectomy.
Journal ArticleDOI
Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual.
Jeffrey E. Gershenwald,Richard A. Scolyer,Kenneth R. Hess,Vernon K. Sondak,Georgina V. Long,M. I. Ross,Alexander J. Lazar,Mark B. Faries,John M. Kirkwood,Grant A. McArthur,Lauren E. Haydu,Alexander M.M. Eggermont,Keith T. Flaherty,Charles M. Balch,John F. Thompson +14 more
TL;DR: The melanoma staging system of the American Joint Committee on Cancer (AJCC) was updated in 2017 as discussed by the authors, with several important changes to the tumor, nodes, metastasis (TNM) classification and stage grouping criteria.
Journal ArticleDOI
Automated Melanoma Recognition in Dermoscopy Images via Very Deep Residual Networks
TL;DR: This study corroborates that very deep CNNs with effective training mechanisms can be employed to solve complicated medical image analysis tasks, even with limited training data.
References
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Journal ArticleDOI
Technical details of intraoperative lymphatic mapping for early stage melanoma.
Donald L. Morton,D. R. Wen,Jan H. Wong,James S. Economou,Leslie A. Cagle,F K Storm,Leland J. Foshag,Alistair J. Cochran +7 more
TL;DR: Patients with early stage melanoma who have nodal metastases and are likely to benefit from radical lymphadenectomy are identified, with a high degree of accuracy, by a new procedure developed using vital dyes.
Journal ArticleDOI
Prognostic Factors Analysis of 17,600 Melanoma Patients: Validation of the American Joint Committee on Cancer Melanoma Staging System
Charles M. Balch,Seng Jaw Soong,Jeffrey E. Gershenwald,John F. Thompson,Douglas S. Reintgen,Natale Cascinelli,Marshall M. Urist,Kelly M. McMasters,M. I. Ross,John M. Kirkwood,Michael B. Atkins,John A. Thompson,Daniel G. Coit,David R. Byrd,Renee A. Desmond,Yuting Zhang,Ping-Yu Liu,Gary H. Lyman,Aberto Morabito +18 more
TL;DR: The proposed tumor-node-metastases categories and stage groupings for cutaneous melanoma patients were validated and incorporated into the AJCC melanoma staging as described in the companion publication.
Journal ArticleDOI
Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma.
TL;DR: The depth of invasion was studied using the criteria for staging of Clark et al.2 to see if maximal cross-sectional area, thickness, stage of invasion, or a combination of these can be of value in assessing the prognosis of cutaneous melanoma.
Journal Article
The Histogenesis and Biologic Behavior of Primary Human Malignant Melanomas of the Skin
TL;DR: Evidence is presented suggesting that superficial spreading melanoma and lentigo maligna melanoma (Hutchinson9s melanotic freckle) show a long period of superficial growth, followed by the relatively rapid appearance of nodules or deeper invasion within the primary lesion.
Journal ArticleDOI
Multi-institutional melanoma lymphatic mapping experience: the prognostic value of sentinel lymph node status in 612 stage I or II melanoma patients.
Jeffrey E. Gershenwald,William A. Thompson,Paul F. Mansfield,Jeffrey E. Lee,Maria I. Colome,Chi-Hong Tseng,J. Jack Lee,Charles M. Balch,Douglas S. Reintgen,Merrick I. Ross +9 more
TL;DR: In this paper, the effect of pathologic sentinel lymph node (SLN) status with that of other known prognostic factors on recurrence and survival in patients with stage I or II cutaneous melanoma was compared.
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