Fish oil supplementation in rheumatoid arthritis
TLDR
Fish oil supplementation could represent a valuable support to the traditional pharmacological treatment of rheumatoid arthritis and the anti-inflammatory effects are linked to the production of alternative eicosanoids.Abstract:
The beneficial properties of fish oil are well known and are related to its fatty acid composition rich in omega-3 polyunsaturated fatty acids. In the last years a variety of epidemiological and clinical studies have demonstrated the efficacy of fish oil supplementation in the rheumatic diseases, in particular in rheumatoid arthritis. The anti-inflammatory effects of fish oil are linked to the production of alternative eicosanoids, to the reduction of proinflammatory cytokines, to the inhibition of the activation of T lymphocytes and of catabolic enzymes. Fish oil supplementation could represent a valuable support to the traditional pharmacological treatment of rheumatoid arthritis.read more
Citations
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Journal ArticleDOI
Rose hip herbal remedy in patients with rheumatoid arthritis – a randomised controlled trial
S.N. Willich,Karin Rossnagel,Stephanie Roll,A. Wagner,O. Mune,J. Erlendson,A. Kharazmi,H. Sörensen,Kaj Winther +8 more
TL;DR: The results indicate that patients with RA may benefit from additional treatment with rose hip powder, according to ARA/ACR criteria.
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Omega-3 polyunsaturated fatty acids in the brain: metabolism and neuroprotection.
TL;DR: The current understanding of the neuroprotective effects of n-3 PUFAs against cerebral ischemia and neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease are highlighted.
Patent
Composition and method to alleviate joint pain using a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated epa and dha
TL;DR: In this article, a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated EPA and DHA either alone or in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.
Patent
Composition and method to alleviate joint pain
TL;DR: In this article, the effects of krill oil and/or marine oil in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form were found to alleviate joint pain and symptoms of osteoarthritis and rheumatoid arthritis.
Ácidos grasos omega-3 (epa y dha) y su aplicación en diversas situaciones clínicas omega-3 fatty acids (epa and dha) and its application in diverse clinical situations
TL;DR: In this article, the authors reviewed possible clinical applications of eicosapentaenoic acid (EPA) and docosahexaenoic acids (DHA) in pathologies, such as cardiovascular and neurodegenerative diseases, cancer, inflammatory bowel disease, rheumatoid arthritis and ischemia -reconstfusion injury.
References
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Journal ArticleDOI
Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial
TL;DR: Dietary supplementation with n-3 PUFA led to a clinically important and statistically significant benefit and vitamin E had no benefit and its effects on fatal cardiovascular events require further exploration.
Journal ArticleDOI
High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors
TL;DR: The increased incidence of CV events in RA patients is independent of traditional CV risk factors, which suggests that additional mechanisms are responsible for CV disease in RA.
Journal ArticleDOI
The Omega-3 Index: a new risk factor for death from coronary heart disease?
TL;DR: In this article, the Omega-3 Index was proposed as a new risk factor for death from coronary heart disease (CHD) and the relationship between this putative marker and risk for CHD death, especially sudden cardiac death (SCD), was evaluated in several published primary and secondary prevention studies.
Journal ArticleDOI
Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Clinical and immunologic effects.
Joel M. Kremer,David A. Lawrence,William Jubiz,Ralph Digiacomo,Richard Rynes,Lee E. Bartholomew,Malcolm J. Sherman +6 more
TL;DR: It is concluded that the clinical benefits of dietary supplementation with omega-3 fatty acids are more commonly observed in patients consuming higher dosages of fish oil for time intervals that are longer than those previously studied.
Journal Article
Fish-Oil Fatty Acid Supplementation in Active Rheumatoid Arthritis
Joel M. Kremer,William Jubiz,Ann Michalek,Richard I. Rynes,Lee E. Bartholomew,Jean Bigaouette,Maryann Timchalk,Donald Beeler,Lloyd Lininger +8 more
TL;DR: In this article, the efficacy of fish-oil dietary supplements in active rheumatoid arthritis and their effect on neutrophil leukotriene levels was evaluated using a nonrandomized, double-blocked setting.
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