Journal ArticleDOI
Fluorinated alternatives to long-chain perfluoroalkyl carboxylic acids (PFCAs), perfluoroalkane sulfonic acids (PFSAs) and their potential precursors
TLDR
It is unclear whether fluorinated alternatives are safe for humans and the environment and three major data gaps are identified that must be filled to perform meaningful risk assessments.About:
This article is published in Environment International.The article was published on 2013-10-01. It has received 602 citations till now.read more
Citations
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A review of the pathways of human exposure to poly- and perfluoroalkyl substances (PFASs) and present understanding of health effects
Elsie M. Sunderland,Xindi C. Hu,Clifton Dassuncao,Andrea K Tokranov,Charlotte C. Wagner,Joseph G. Allen +5 more
TL;DR: Understanding of sources and trends in human exposure to poly- and perfluoroalkyl substances (PFASs) and epidemiologic evidence for impacts on cancer, immune function, metabolic outcomes, and neurodevelopment are reviewed.
Journal ArticleDOI
A Never-Ending Story of Per- and Polyfluoroalkyl Substances (PFASs)?
TL;DR: Recommendations for how to proceed with research and cooperation to tackle the vast number of PFASs on the market and in the environment are provided.
Journal ArticleDOI
Global emission inventories for C4-C14 perfluoroalkyl carboxylic acid (PFCA) homologues from 1951 to 2030, Part I: production and emissions from quantifiable sources.
TL;DR: This work quantifies global emissions of C4-C14 perfluoroalkyl carboxylic acid (PFCA) homologues during the life-cycle of products based on perfluorooctanoic Acid (PFOA), perfLUorononanoic acid (PFNA), perfluarooctane sulfonyl fluoride (POSF), and fluorotelomer compounds, and addresses the uncertainties of the PFCA emissions by defining a lower
Journal ArticleDOI
An overview of the uses of per- and polyfluoroalkyl substances (PFAS)
Juliane Glüge,Martin Scheringer,Ian T. Cousins,Jamie C. DeWitt,Gretta Goldenman,Dorte Herzke,Rainer Lohmann,Carla A. Ng,Xenia Trier,Zhanyun Wang +9 more
TL;DR: This study clearly demonstrates that PFAS are used in almost all industry branches and many consumer products, and more than 200 use categories and subcategories are identified for more than 1400 individual PFAS.
References
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Journal ArticleDOI
Perfluoroalkyl and polyfluoroalkyl substances in the environment: Terminology, classification, and origins
Robert C. Buck,James Franklin,Urs Berger,Jason M. Conder,Ian T. Cousins,Pim de Voogt,Allan Astrup Jensen,Kurunthachalam Kannan,Scott A. Mabury,Stefan P.J. van Leeuwen +9 more
TL;DR: An overview of PFASs detected in the environment, wildlife, and humans, and recommend clear, specific, and descriptive terminology, names, and acronyms for PFAS, can be found in this article.
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Global distribution of perfluorooctane sulfonate in wildlife.
TL;DR: Fish-eating, predatory animals such as mink and bald eagles contained concentrations of PFOS that were greater than the concentrations in their diets, suggesting that PFOS can bioaccumulate to higher trophic levels of the food chain.
Journal ArticleDOI
Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
Christopher Lau,Katherine Anitole,Colette Hodes,David Y. Lai,Andrea Pfahles-Hutchens,Jennifer Seed +5 more
TL;DR: An overview of the recent advances in the toxicology and mode of action for PFAAs, and of the monitoring data now available for the environment, wildlife, and humans is provided.
Journal ArticleDOI
Sources, fate and transport of perfluorocarboxylates.
TL;DR: Transport pathways for PFCAs in the environment were reviewed, and it was concluded that, in addition to atmospheric transport/degradation of precursors, atmospheric and ocean water transport of the PFCA themselves could significantly contribute to their long-range transport.
Journal ArticleDOI
Half-life of serum elimination of perfluorooctanesulfonate,perfluorohexanesulfonate, and perfluorooctanoate in retired fluorochemical production workers.
Geary W. Olsen,Jean M. Burris,David J. Ehresman,John W. Froehlich,Andrew M. Seacat,John L. Butenhoff,Larry R. Zobel +6 more
TL;DR: Humans appear to have a long half-life of serum elimination of PFOS, PFHS, and PFOA, which may be due, in part, to a saturable renal resorption process.