Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
Christopher Lau,Katherine Anitole,Colette Hodes,David Y. Lai,Andrea Pfahles-Hutchens,Jennifer Seed +5 more
TLDR
An overview of the recent advances in the toxicology and mode of action for PFAAs, and of the monitoring data now available for the environment, wildlife, and humans is provided.About:
This article is published in Toxicological Sciences.The article was published on 2007-10-01 and is currently open access. It has received 2175 citations till now.read more
Citations
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Journal ArticleDOI
Perfluoroalkyl and polyfluoroalkyl substances in the environment: Terminology, classification, and origins
Robert C. Buck,James Franklin,Urs Berger,Jason M. Conder,Ian T. Cousins,Pim de Voogt,Allan Astrup Jensen,Kurunthachalam Kannan,Scott A. Mabury,Stefan P.J. van Leeuwen +9 more
TL;DR: An overview of PFASs detected in the environment, wildlife, and humans, and recommend clear, specific, and descriptive terminology, names, and acronyms for PFAS, can be found in this article.
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Polyfluorinated Compounds: Past, Present, and Future
TL;DR: The utility of these compounds seems to ensure their continued use in one form or another for the foreseeable future, presenting a long-term challenge to scientists, industry leaders, and public health officials worldwide.
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The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system.
TL;DR: This review will be aimed at providing an overview of the current knowledge on the involvement of the chemokine/chemokine-receptor system in the cytokine storm related to SARS-CoV-2 infection.
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Perfluorinated compounds--exposure assessment for the general population in Western countries.
TL;DR: Overall, the contribution of PFOS and PFOA precursors to total exposure seems to be limited, and besides this background exposure of the general population, a specific additional exposure may occur which causes an increased PFC body burden.
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Fate and toxicity of emerging pollutants, their metabolites and transformation products in the aquatic environment
TL;DR: In this article, the authors review the fate and the ecotoxicology of emerging pollutants, especially focusing on their metabolites and transformation products (TPs) in the aquatic environment, including pharmaceuticals, hormones, perfluorinated compounds, byproducts of drinking-water disinfection, sunscreens or UV filters, benzotriazoles and naphthalenic acids.
References
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Global distribution of perfluorooctane sulfonate in wildlife.
TL;DR: Fish-eating, predatory animals such as mink and bald eagles contained concentrations of PFOS that were greater than the concentrations in their diets, suggesting that PFOS can bioaccumulate to higher trophic levels of the food chain.
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Sources, fate and transport of perfluorocarboxylates.
TL;DR: Transport pathways for PFCAs in the environment were reviewed, and it was concluded that, in addition to atmospheric transport/degradation of precursors, atmospheric and ocean water transport of the PFCA themselves could significantly contribute to their long-range transport.
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Half-life of serum elimination of perfluorooctanesulfonate,perfluorohexanesulfonate, and perfluorooctanoate in retired fluorochemical production workers.
Geary W. Olsen,Jean M. Burris,David J. Ehresman,John W. Froehlich,Andrew M. Seacat,John L. Butenhoff,Larry R. Zobel +6 more
TL;DR: Humans appear to have a long half-life of serum elimination of PFOS, PFHS, and PFOA, which may be due, in part, to a saturable renal resorption process.
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Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators.
Susanna S.T. Lee,Thierry Pineau,John Drago,Eric J. Lee,Jennie W. Owens,Deanna L. Kroetz,Pedro M. Fernández-Salguero,Heiner Westphal,Frank J. Gonzalez +8 more
TL;DR: It is demonstrated that mPPAR alpha is the major isoform required for mediating the pleiotropic response resulting from the actions of peroxisome proliferators.
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Biological Monitoring of Polyfluoroalkyl Substances: A Review
TL;DR: The pattern of contamination in wildlife varied among species and locations suggesting multiple emission sources and knowledge gaps with respect to the transport, accumulation, biodegradation, temporal/spatial trends and PFS precursors have been identified.