Journal ArticleDOI
Formation of nexuses and electrotonic transmission between myocardial and FL cells in monolayer culture.
TLDR
Electron microscopy showed nexuses in the regions of intercellular contact between myocardial and FL cells and between FL cells.About:
This article is published in Experimental Cell Research.The article was published on 1970-11-01. It has received 97 citations till now. The article focuses on the topics: Depolarization.read more
Citations
More filters
Journal ArticleDOI
Structural and functional characterisation of cardiac fibroblasts
TL;DR: This review summarizes the understanding of fibroblast origin and identity, their structural organization and role in myocardial architecture, as well as functional aspects related to cell signalling and electro-mechanical function in the heart.
Journal ArticleDOI
Coupling of cardiac electrical activity over extended distances by fibroblasts of cardiac origin
TL;DR: It is illustrated that fibroblasts of cardiac origin are capable of synchronizing electrical activity of multicellular cardiac tissue over extended distances through electrotonic interactions, accompanied by extremely large local conduction delays, which might contribute to the generation of arrhythmias in fibrotic hearts.
Journal ArticleDOI
Intramyocardial Fibroblast Myocyte Communication
Rahul Kakkar,Richard T. Lee +1 more
TL;DR: This review discusses the most recent concepts in cardiac fibroblast-myocyte communication and areas of potential future research.
Journal ArticleDOI
Stretch-induced changes in heart rate and rhythm: clinical observations, experiments and mathematical models
TL;DR: The clinical relevance of mechano-electric feedback, cellular correlates to the responses observed in situ, and the role that quantitative mathematical models may play in identifying the involvement of cardiac MEF in the regulation of heart rate and rhythm are outlined.
References
More filters
Journal ArticleDOI
THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY
TL;DR: The stain reported here differs from previous alkaline lead stains in that the chelating agent, citrate, is in sufficient excess to sequester all lead present, and is less likely to contaminate sections.
Journal ArticleDOI
Junctional complexes in various epithelia
TL;DR: The tight junction is impervious to concentrated protein solutions and appears to function as a diffusion barrier or "seal," and the desmosome and probably also the zonula adhaerens may represent intercellular attachment devices.
Journal ArticleDOI
Hexagonal array of subunits in intercellular junctions of the mouse heart and liver.
TL;DR: A new technique, based on the observations of Doggenweiler and Frenks, wMch has allowed us to demonstrate the presence of similar structures in sections of mouse heart and of mouse liver, and it seems likely that, as lanthanum solutions are brought to a high pH, a colloidal compound is formed which permeates the extracellular space as a tracer.
Journal ArticleDOI
STUDIES ON AN EPITHELIAL (GLAND) CELL JUNCTION I. Modifications of Surface Membrane Permeability
TL;DR: Membrane permeability of an epithelial cell junction (Drosophila salivary gland) was examined with intracellular microelectrodes and with fluorescent tracers and the organ here, rather than the single cell, appears to be the unit of ion environment.
Journal ArticleDOI
Propagation of Action Potentials and the Structure of the Nexus in Cardiac Muscle
Lloyd Barr,M. M. Dewey,W. Berger +2 more
TL;DR: Electron micrographs demonstrate that the nexuses of frog atrium and guinea pig ventricle are ruptured by hypertonic solutions.