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Open AccessJournal ArticleDOI

From NLR to TIN: What Can’t Neutrophils Tell Us About Prognosis in Resectable Esophageal Cancer?

Nathaniel Deboever, +1 more
- 06 Jan 2023 - 
- Vol. 30, Iss: 3, pp 1-2
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This article is published in Annals of Surgical Oncology.The article was published on 2023-01-06 and is currently open access. It has received 0 citations till now. The article focuses on the topics: Medicine & Surgical oncology.

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Journal ArticleDOI

IFN- γ –related mRNA profile predicts clinical response to PD-1 blockade

TL;DR: The T cell–inflamed GEP contained IFN-&ggr;–responsive genes related to antigen presentation, chemokine expression, cytotoxic activity, and adaptive immune resistance, and these features were necessary, but not always sufficient, for clinical benefit.
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The tumor microenvironment and its role in promoting tumor growth.

TL;DR: The tumor microenvironment is created by the tumor and dominated by tumor-induced interactions, and various immune effector cells are recruited to the tumor site, their anti-tumor functions are downregulated, largely in response to tumor-derived signals.
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Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment modalities

TL;DR: Tumor markers of esophageal cancer are an advancing area of research that could potentially lead to earlier diagnosis as well as playing a part in assessing tumor response to therapy.
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The prognostic value of tumor-infiltrating neutrophils in gastric adenocarcinoma after resection.

TL;DR: The presence of CD15+ TINs is an independent and unfavorable factor in the prognosis of gastric adenocarcinoma patients and Targeting CD15-TINs may be a potential intervenient therapy in the future.
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MSI as a predictive factor for treatment outcome of gastroesophageal adenocarcinoma

TL;DR: The value of conventional cytotoxic treatment in MSI-H tumors is unclear and results on its efficacy range from detrimental to beneficial effects.
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