Generalized juvenile gastrointestinal polyposis. A hereditary syndrome.
TLDR
A classification of hereditary polypoid diseases of the gastrointestinal tract is proposed, using the microscopic characteristics of the polyps per se as the basis for delineating the several distinct syndromes.About:
This article is published in Gastroenterology.The article was published on 1970-05-01 and is currently open access. It has received 104 citations till now. The article focuses on the topics: Juvenile gastrointestinal polyposis & Peutz–Jeghers syndrome.read more
Citations
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Journal ArticleDOI
Bannayan-Riley-Ruvalcaba syndrome.
TL;DR: The phenotypic spectrum is expanded to include Hashimoto thyroiditis, which occurred in 7 of 10 cases of Bannayan-Riley-Ruvalcaba syndrome, and the relationship between the syndrome and juvenile polyposis of infancy is discussed.
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Juvenile polyposis and gastrointestinal carcinoma. A study of a kindred.
TL;DR: The pattern of inheritance in this kindred suggests either a single or two closely linked autosomal dominant determinants for gastrointestinal carcinoma and polyposis.
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Familial juvenile polyposis coli; increased risk of colorectal cancer.
H Järvinen,K O Franssila +1 more
TL;DR: The histological changes in colonic polyps formed a spectrum from juvenile polyps, through focal to extensive adenomatous change, to adenocarcinomas, which contradict the previous view that juvenile polyposis coli is not premalignant and only rarely needs surgical treatment.
Journal ArticleDOI
Malignant potential in intestinal juvenile polyposis syndromes.
TL;DR: This study shows that juvenile polyposis syndromes carry a more significant risk of carcinoma than generally appreciated and more intense endoscopic surveillance may be warranted, and definitive surgical options should often be considered in these syndrome.
Journal ArticleDOI
Juvenile polyposis syndrome
Lodewijk A.A. Brosens,Danielle Langeveld,Danielle Langeveld,W. Arnout van Hattem,Francis M. Giardiello,G. Johan A. Offerhaus,G. Johan A. Offerhaus +6 more
TL;DR: Juvenile polyposis syndrome is a rare autosomal dominant syndrome characterized by multiple distinct juvenile polyps in the gastrointestinal tract and an increased risk of colorectal cancer.
References
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Multiple cutaneous and subcutaneous lesions occurring simultaneously with hereditary polyposis and osteomatosis.
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Malignant tumors of the central nervous system associated with familial polyposis of the colon: report of two cases.
TL;DR: Turcot syndrome is the association between familial adenomatous polyposis and brain tumors like medulloblastoma, malignant glioma, and hence carries the first author's name.
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Association of Thyroid Carcinoma with Gardner's Syndrome in Siblings
TL;DR: The records are documenting the records of two sisters with Gardner's syndrome each of whom also had thyroid carcinoma, in view of the familial setting of their major illness.