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Genomic Epidemiology of Global Carbapenemase-Producing Escherichia coli, 2015–2017

TLDR
The E. coli population is dominated by diverse sequence types with varied geographic distributions, warranting ongoing genomic surveillance.
Abstract
The E. coli population is dominated by diverse sequence types with varied geographic distributions, warranting ongoing genomic surveillance.

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Escherichia coli ST1193: Following in the Footsteps of E. coli ST131

TL;DR: Basic mechanistic, evolutionary, surveillance, and clinical studies are urgently required to investigate the success of ST1193, an emerging global multidrug (MDR) high-risk clone and an important cause of community-onset urinary and bloodstream infections.
Journal ArticleDOI

OXA-48-Like β-Lactamases: Global Epidemiology, Treatment Options, and Development Pipeline

TL;DR: The molecular machinery enabling global spread, current treatment options, and the development pipeline of potential new therapies for Enterobacterales that produce OXA-48-like β-lactamases form the focus of this review.
Journal ArticleDOI

Acquisition of genomic elements were pivotal for the success of Escherichia coli ST410.

TL;DR: The global ST410 population producing carbapenemases is dominated by the ST410-B2 and B3 subclades with varied geographical distribution that requires ongoing genomic surveillance.
Journal ArticleDOI

Molecular surveillance of multidrug-resistant Gram-negative bacteria in Ukrainian patients, Germany, March to June 2022

TL;DR: In this article , the authors investigated the prevalence and the molecular epidemiology of multidrug-resistant Gram-negative (MDRGN) bacteria and meticillin-resistant Staphylococcus aureus (MRSA) in Ukrainian patients at admission to the University Hospital Frankfurt, Germany.
References
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Journal Article

R: A language and environment for statistical computing.

R Core Team
- 01 Jan 2014 - 
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
Journal ArticleDOI

Controlling the false discovery rate: a practical and powerful approach to multiple testing

TL;DR: In this paper, a different approach to problems of multiple significance testing is presented, which calls for controlling the expected proportion of falsely rejected hypotheses -the false discovery rate, which is equivalent to the FWER when all hypotheses are true but is smaller otherwise.
Journal ArticleDOI

RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies.

TL;DR: This work presents some of the most notable new features and extensions of RAxML, such as a substantial extension of substitution models and supported data types, the introduction of SSE3, AVX and AVX2 vector intrinsics, techniques for reducing the memory requirements of the code and a plethora of operations for conducting post-analyses on sets of trees.

Performance standards for antimicrobial susceptibility testing

TL;DR: The supplemental information presented in this document is intended for use with the antimicrobial susceptibility testing procedures published in the following Clinical and Laboratory Standards Institute (CLSI)–approved standards.
Journal ArticleDOI

Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees

TL;DR: ITOL 3 is the first tool which supports direct visualization of the recently proposed phylogenetic placements format, and its account system has been redesigned to simplify the management of trees in user-defined workspaces and projects.
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