Journal ArticleDOI
Growth Delay in Postburn Pediatric Patients
Randi L. Rutan,David N. Herndon +1 more
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TLDR
It is demonstrated that severe thermal injury is associated with a growth delay in the pediatric population and the exact cause of this phenomenon remains unknown.Abstract:
• Dampened height and weight velocities have been observed in our postburn pediatric population. To validate this phenomenon, the medical records of 80 patients who had sustained a greater than 40% total body surface area burn, were older than 2 years of age at the time of the burn, and were at least 1 year post burn were reviewed. All patients were treated with early excision of the burn wound within 72 hours of injury and received standard post burn resuscitational and nutritional support. Admission height and weight plots were within normal distribution parameters. Yearly growth velocities were calculated for up to 3 years after the burn. Despite adequate nutritional support and maximal exercise and/or long-bone stresses, a profound growth arrest was noted during postburn year 1, which slowly resolved to near normal distribution by postburn year 3. This retrospective study demonstrates that severe thermal injury is associated with a growth delay in the pediatric population. The exact cause of this phenomenon remains unknown. ( Arch Surg. 1990;125:392-395)read more
Citations
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Persistence of muscle catabolism after severe burn
David W. Hart,Steven E. Wolf,Ronald P. Mlcak,David L. Chinkes,Peter I. Ramzy,Michael K. Obeng,Arny A. Ferrando,Robert R. Wolfe,David N. Herndon +8 more
TL;DR: In severely burned children, hypermetabolism and catabolism remain exaggerated for at least 9 months after injury, suggesting that therapeutic attempts to manipulate the catabolic and hypermetabolic response to severe injury should be continued long after injury.
Journal ArticleDOI
Support of the metabolic response to burn injury
TL;DR: Exogenous continuous low-dose insulin infusion, beta blockade with propranolol, and use of the synthetic testosterone analogue oxandrolone are the most cost effective and least toxic pharmacological treatments to date.
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Why are nutritionally stunted children at increased risk of obesity? Studies of metabolic rate and fat oxidation in shantytown children from São Paulo, Brazil
Daniel J. Hoffman,Ana Lydia Sawaya,Ieda Therezinha do Nascimento Verreschi,Katherine L. Tucker,S. B. Roberts +4 more
TL;DR: In this paper, the authors found that childhood nutritional stunting is associated with impaired fat oxidation, a factor that predicted obesity in other at-risk populations, which may help explain recent increases in body fatness and the prevalence of obesity among stunted adults and adolescents in developing countries.
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Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy.
Thomas W. Buford,Stephen D. Anton,Andrew Judge,Emanuele Marzetti,Stephanie E. Wohlgemuth,Christy S. Carter,Christiaan Leeuwenburgh,Marco Pahor,Todd M. Manini +8 more
TL;DR: This review discusses how factors common to older individuals such as cancer, kidney disease, diabetes, and peripheral artery disease affect systemic and cellular mechanisms that contribute to skeletal muscle atrophy and describes gaps in the literature concerning the role of these factors in accelerating sarcopenia progression.
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Prevalence of malnutrition in pediatric hospital patients.
TL;DR: The prevalence of acute malnutrition of children admitted to hospital is still considerably high, but there is a scarcity of data concerning the nutritional status during hospital admission, and screening tools to identify children at risk of developing malnutrition might be helpful.
References
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Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. II
TL;DR: The solution to the alternatives of plotting against chronological or developmental age at adolescence is adopted and centiles plotted against chronological age over the whole age span are given.
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Physical growth: National Center for Health Statistics percentiles.
TL;DR: The new National Center for Health Statistics percentiles can be used to improve identification of potential health and nutritional problems and to facilitate the epidemological comparison of one group of children with others.
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Carbohydrate metabolism in man: effect of elective operations and major injury.
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Alterations in hypothalamic function following thermal injury.
TL;DR: In this paper, nine burn patients with a mean burn size of 39% (range, 23-65%) and five normal individuals studied in an environmental chamber selected optimal comfort temperature by regulating a bedside temperature control unit.