M
Marco Pahor
Researcher at University of Florida
Publications - 488
Citations - 52446
Marco Pahor is an academic researcher from University of Florida. The author has contributed to research in topics: Randomized controlled trial & Population. The author has an hindex of 112, co-authored 476 publications receiving 46549 citations. Previous affiliations of Marco Pahor include Stanford University & Northwestern University.
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Journal ArticleDOI
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
David E. Harrison,Randy Strong,Zelton D Sharp,James F. Nelson,Clinton M. Astle,Kevin Flurkey,Nancy L. Nadon,J. Erby Wilkinson,Krystyna Frenkel,Christy S. Carter,Christy S. Carter,Marco Pahor,Marco Pahor,Martin A. Javors,Elizabeth Fernandez,Richard A. Miller +15 more
TL;DR: It is reported that rapamycin, an inhibitor of the mTOR pathway, extends median and maximal lifespan of both male and female mice when fed beginning at 600 days of age.
Journal ArticleDOI
Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults.
Kim Sutton-Tyrrell,Samer S. Najjar,Robert M. Boudreau,Lakshmi Venkitachalam,Varant Kupelian,Eleanor M. Simonsick,Richard J. Havlik,Edward G. Lakatta,Harold A. Spurgeon,Stephen B. Kritchevsky,Marco Pahor,Douglas C. Bauer,Anne B. Newman +12 more
TL;DR: Among generally healthy, community-dwelling older adults, aPWV, a marker of arterial stiffness, is associated with higher CV mortality, CHD, and stroke.
Journal ArticleDOI
Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial
Marco Pahor,Jack M. Guralnik,Jack M. Guralnik,Walter T. Ambrosius,Steven N. Blair,Denise E. Bonds,Timothy S. Church,Mark A. Espeland,Roger A. Fielding,Thomas M. Gill,Erik J. Groessl,Erik J. Groessl,Abby C. King,Stephen B. Kritchevsky,Todd M. Manini,Mary M. McDermott,Michael E. Miller,Anne B. Newman,W. Jack Rejeski,Kaycee M. Sink,Jeff D. Williamson +20 more
TL;DR: The findings suggest mobility benefit from a structured, moderate-intensity physical activity program compared with a health education program reduced major mobility disability over 2.6 years among older adults at risk for disability.
Journal ArticleDOI
Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis
Bruce M. Psaty,Thomas Lumley,Curt D. Furberg,Gina D. Schellenbaum,Marco Pahor,Michael H. Alderman,Noel S. Weiss +6 more
TL;DR: Low-dose diuretics are the most effective first-line treatment for preventing the occurrence of cardiovascular disease morbidity and mortality and future trials should use low-doseDiuretics as the standard for clinically useful comparisons.
Journal ArticleDOI
Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial.
Stephen P. Messier,Richard F. Loeser,Gary D. Miller,Timothy M. Morgan,W. Jack Rejeski,Mary Ann Sevick,Walter H. Ettinger,Marco Pahor,Jeff D. Williamson +8 more
TL;DR: The combination of modest weight loss plus moderate exercise provides better overall improvements in self-reported measures of function and pain and in performance measures of mobility in older overweight and obese adults with knee OA compared with either intervention alone.