Journal ArticleDOI
Helix–coil transition in poly(γ‐benzyl‐L‐glutamate) and poly‐ε‐carbobenzoxy‐L‐lysine
TLDR
In this article, the helical content of poly(γ-benzyl-L-glutamate) was calculated using the transition from experimental data and its interpretation, and the parameter ΔH obtained was in good agreement with the calorimetric one and v was found to be independent of temperature and solvent.Abstract:
In this paper two points are considered: the methods of evaluating the helical content θ and the calculation of the parameters of the transition from experimental data and its interpretation. The parameter ΔH obtained is in good agreement with the calorimetric one and v is found to be independent of temperature and solvent and in agreement with the ordinarily accepted value for poly(γ-benzyl-L-glutamate). The different methods of estimating θ are discussed for both polypeptides.read more
Citations
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Journal ArticleDOI
Cooperative conformational transitions of linear biopolymers.
Jürgen Engel,Gerhard Schwarz +1 more
TL;DR: Conformational transitions in proteins, nucleic acids, and other biopolymers evidently play a decisive role in many biological processes, particularly in control processes, and the resulting equilibrium properties of cooperative systems can be quantitatively explained for linear systems by the linear Ising model.
Journal ArticleDOI
Kooperative Konformationsumwandlungen von linearen Biopolymeren
Jürgen Engel,Gerhard Schwarz +1 more
TL;DR: In this article, a linearen Ising-modelled Makromolekule is presented, in which the Molekularen Ursachen der Kooperativitat konnen fur einfache Modellpolymere gedeutet werden.
Journal ArticleDOI
Calorimetric measurement of enthalpy change in the isothermal helix–coil transition of poly(L‐ornithine) in aqueous solution
Peter Y. Chou,Harold A. Scheraga +1 more
TL;DR: Since it was discovered that poly(L‐ornithine) undergoes chain cleavage at high pH, the calorimetric measurements were carried out under conditions where no degradation occurred.
Journal ArticleDOI
Cooperative transition between two helical conformations in a linear system: Poly-L-proline I ⇌ II. I. Equilibrium studies
TL;DR: In this article, the solvent-induced conformational transition between the two helical forms of poly-L-proline is studied as a model for cooperative order ⇌ order transitions.
Journal ArticleDOI
Solution properties of synthetic polypeptides. XV. Helix–coil transition in poly (ε-carbobenzyloxy L-lysine)
TL;DR: In this paper, the helical content of poly(e-carbobenzyloxy L-lysine) (PCBL) in m-cresol and in mixtures of dichloroacetic acid (DCA) and ethylene dichloride (EDC) were investigated by optical rotation measurements.
References
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Journal ArticleDOI
Theory of the Phase Transition between Helix and Random Coil in Polypeptide Chains
Bruno H. Zimm,J. K. Bragg +1 more
TL;DR: In this paper, the transition between the helical and randomly coiled forms of a polypeptide chain is discussed by reference to a simple model that allows bonding only between each group and the third preceding.
Journal ArticleDOI
On the Theory of Helix—Coil Transition in Polypeptides
Shneior Lifson,A. Roig +1 more
TL;DR: In this paper, the conditional probabilities of occurrence of helical and coiled states of the peptide units were obtained in the form of a 3×3 matrix and the order of this matrix is the lowest possible for the model employed, and is derived by a logical procedure which serves to eliminate redundancies in the enumeration of states.
Journal ArticleDOI
Optical Rotatory Dispersion of Helical Polymers
TL;DR: In this paper, it was shown that for every transition in its individual residues, a helix has two transitions whose moments are respectively parallel and perpendicular to the screw axis, and that the largest contributions to the rotational strengths of these bands are equal and opposite in the two cases.
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Theory of the Phase Transition between Helix and Random Coil in Polypeptide Chains
Bruno H. Zimm,J. K. Bragg +1 more