Human cardiac transplantation: clinical experience.
Michael E. De Bakey,Edward B. Diethrich,Gerald Glick,George P. Noon,William T. Butler,Roger D. Rossen,John E. Liddicoat,David K. Brooks +7 more
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This article is published in The Journal of Thoracic and Cardiovascular Surgery.The article was published on 1969-09-01 and is currently open access. It has received 29 citations till now. The article focuses on the topics: Transplantation.read more
Citations
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Rate of Calcium Binding and Uptake in Normal Animal and Failing Human Cardiac Muscle
Shoichi Harigaya,Arnold Schwartz +1 more
TL;DR: ATP was the most effective of four nucleoside triphosphates in supporting calcium binding and uptake and mitochondria accumulated calcium at a rate faster than CRS.
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Rate of Calcium Binding and Uptake in Normal Animal and Failing Human Cardiac Muscle: MEMBRANE VESICLES (RELAXING SYSTEM) AND MITOCHONDRIA
Shoichi Harigaya,Arnold Schwartz +1 more
TL;DR: In this paper, a modified rapid procedure was used to isolate the cardiac relaxing system (CRS) and mitochondria from human, rabbit, and dog, and the estimated initial binding rates (nmoles calcium/mg protein/minute) were 256, 1440 and 182, respectively.
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Hemodynamic observations one and two years after cardiac transplantation in man.
TL;DR: These studies demonstrate the sustained capacity of the transplanted human heart to support normal physical activity late in the postoperative period and demonstrate atypical adaptive mechanisms characteristic of the denervated heart responds in a directionally appropriate manner to the metabolic demands of exercise.
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Outcomes in cardiac transplant recipients using allografts from older donors versus mortality on the transplant waiting list: Implications for donor selection criteria
TL;DR: Despite a strong association between older donor age and increased post-operative mortality and TCAD, it is more beneficial in terms of patient survival to receive an allograft from a donor >40 years old than to remain on the waiting list.
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Relation of Donor Age and Preexisting Coronary Artery Disease on Angiography and Intracoronary Ultrasound to Later Development of Accelerated Allograft Coronary Artery Disease
TL;DR: Preexisting coronary artery disease, nonuse of calcium channel blocking agents, older donor age, posttransplantation cytomegalovirus infection, elevated very low density lipoprotein levels and previous ischemic heart disease in the recipient were significant predictors of allograft coronary artery Disease.
References
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Journal Article
The operation. a human cardiac transplant: an interim report of a successful operation performed at groote schuur hospital, cape town
TL;DR: The first human heart transplant is describedbed.com, and the operative technique is detailed.
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Homovital transplantation of the heart.
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Homovital transplantation of the heart
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Glucagon Its Enhancement of Cardiac Performance in the Cat and Dog and Persistence of its Inotropic Action Despite Beta-Receptor Blockade with Propranolol
TL;DR: In the dog, myocardial performance was markedly augmented by the administration of glucagon, 50 μg/kg iv, as indicated by an average increase of 72.2±18.8% in force recorded by a strain gauge arch, despite an average decrease of 3.8±1.2 cm H2O (P < 0.02) in left ventricular end-diastolic pressure.
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Heart transplantation in man. developmental studies and report of a case.
James D. Hardy,Chavez Cm,Fred D. Kurrus,William A. Neely,Sadan Eraslan,M. Don Turner,Leonard W. Fabian,Thaddeus D. Labecki +7 more
TL;DR: The laboratory and clinical heart work justified a planned approach directed toward eventual heart transplantation in man and this objective, a natural outgrowth of transplantation research, was cleared with the administrative officials of the University Medical Center.