Journal ArticleDOI
Human liver mitochondria.
Kazue Ozawa,Osamu Kitamura,Tomoo Mizukami,Yoshio Yamaoka,Takakazu Kamano,Hlroshi Takeda,Hidenari Takasan,Ichio Honjo +7 more
TLDR
A systematic method has been presented for quantitatively estimating the respiratory pigments without complete removal of hemoglobin in mitochondria prepared by the procedure commonly applied to rat liver and no statistically significant decline in the phosphorylation rates with increasing age could be demonstrated.About:
This article is published in Clinica Chimica Acta.The article was published on 1972-05-01. It has received 86 citations till now. The article focuses on the topics: Cytochrome c & Cytochrome.read more
Citations
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On the importance of fatty acid composition of membranes for aging.
TL;DR: The membrane pacemaker theory of aging is an extension of the oxidative stress theory of Aging which emphasises variation in the fatty acid composition of membranes as an important influence on lipid peroxidation and consequently on the rate of aging and determination of lifespan.
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Measurement of cytochromes in human skeletal muscle mitochondria, isolated from fresh and frozen stored muscle specimens.
TL;DR: It is concluded that human mitochondrial suspensions are contaminated with hemoglobin or myoglobin, and cytochrome content calculated after reduction of the cytochromes with succinate plus KCN is lower than that obtained after reduction with dithionite, indicating incomplete reduction by the former method.
Journal ArticleDOI
Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition
Fabio Di Lisa,Paolo Bernardi +1 more
TL;DR: This work analyzes the possible mechanisms through which PTP opening might contribute to age-related myocardial alterations and the available evidence of an increased probability of PTPOpening in mitochondria isolated from aged tissues and examines the current methodological limitations that complicate the elucidation of causal relationships between PTPopening, mitochondrial dysfunction, and myocardials aging.
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Significance of Blood Ketone Body Ratio as an Indicator of Hepatic Cellular Energy Status in Jaundiced Rabbits
TL;DR: It is suggested that the ratio of acetoacetate to beta-hydroxybutyrate in blood can reflect the energy charge of the liver in jaundiced rabbits.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Inhibition of electron and energy transfer in mitochondria. I. Effects of Amytal, thiopental, rotenone, progesterone, and methylene glycol.
Britton Chance,Gunnar Hollunger +1 more
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Studies on bacterial photophosphorylation. III. A sensitive and rapid method of determination of photophosphorylation.
TL;DR: A new, rapid and sensitive method of determination of the rate and the amount of photophosphorylation with a sensitive recording pH meter is described and the rates determined are in good agreement with values determined by direct phosphate analysis.
Journal ArticleDOI
The reversible removal of cytochrome c from mitochondria.
Earl E. Jacobs,D.R. Sanadi +1 more