Y
Yoshio Yamaoka
Researcher at Kyoto University
Publications - 315
Citations - 14597
Yoshio Yamaoka is an academic researcher from Kyoto University. The author has contributed to research in topics: Transplantation & Liver transplantation. The author has an hindex of 62, co-authored 315 publications receiving 14069 citations. Previous affiliations of Yoshio Yamaoka include University of Cologne & Ehime University.
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Journal ArticleDOI
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
Seiji Satoh,Yataro Daigo,Yoichi Furukawa,Tatsushi Kato,Nobutomo Miwa,Tadashi Nishiwaki,Teru Kawasoe,Hideyuki Ishiguro,Manabu Fujita,Takashi Tokino,Yo Sasaki,Shingi Imaoka,Masaru Murata,Takashi Shimano,Yoshio Yamaoka,Yusuke Nakamura +15 more
TL;DR: Adenovirus mediated gene transfer of wild-type AXIN1 induced apoptosis in hepatocellular and colorectal cancer cells that had accumulated β-catenin as a consequence of either APC, CTNNB1 orAXIN1 mutation, suggesting that axin may be an effective therapeutic molecule for suppressing growth of hepato cellular andcolorectAL cancers.
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Surgical techniques and innovations in living related liver transplantation.
K. Tanaka,Shinji Uemoto,Yukihiko Tokunaga,Shiro Fujita,Kaoru Sano,Takashi Nishizawa,Hisashi Sawada,Isao Shirahase,Hong Jin Kim,Yoshio Yamaoka +9 more
TL;DR: It is suggested that the meticulous management of surgical factors at each stage of the LRLT procedure is crucial for successful outcome and may be regarded as an independent modality to supplement cadaver donation.
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Tumor size predicts vascular invasion and histologic grade: Implications for selection of surgical treatment for hepatocellular carcinoma
Timothy M. Pawlik,Keith A. Delman,Jean Nicolas Vauthey,David M. Nagorney,Irene Oi-Lin Ng,Iwao Ikai,Yoshio Yamaoka,Jacques Belghiti,Gregory Y. Lauwers,Ronnie T.P. Poon,Eddie K. Abdalla +10 more
TL;DR: In this article, the authors examined the relationship between HCC tumor size and microscopic vascular invasion and histologic grade in a multicenter international database of 1,073 patients who underwent resection of HCC.
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Thioredoxin-dependent Redox Regulation of p53-mediated p21 Activation
Masaya Ueno,Hiroshi Masutani,Roberto J. Arai,Akira Yamauchi,Kiichi Hirota,Toshiyuki Sakai,Takashi Inamoto,Yoshio Yamaoka,Junji Yodoi,Toshio Nikaido +9 more
TL;DR: TRX-dependent redox regulation of p53 activity indicates coupling of the oxidative stress response and p53-dependent repair mechanism.
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Reevaluation of prognostic factors for survival after liver resection in patients with hepatocellular carcinoma in a Japanese nationwide survey.
Iwao Ikai,Shigeki Arii,Masamichi Kojiro,Takafumi Ichida,Masatoshi Makuuchi,Yutaka Matsuyama,Yasuni Nakanuma,Kiwamu Okita,Masao Omata,Kenichi Takayasu,Yoshio Yamaoka +10 more
TL;DR: Advances in the diagnosis and surgical treatment of hepatocellular carcinoma have improved the prognosis for patients with HCC who undergo liver resection, and a nationwide data base was evaluated to evaluate prognostic predictors.