Humoral factors affecting pulmonary inflation during acute anaphylaxis in the guinea-pig in vivo.
H. O. J. Collier,G. W. L. James +1 more
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This article is published in British journal of pharmacology and chemotherapy.The article was published on 1967-06-01 and is currently open access. It has received 103 citations till now.read more
Citations
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Journal ArticleDOI
Release of Additional Factors in Anaphylaxis and its Antagonism by Anti-inflammatory Drugs
Priscilla J. Piper,John R. Vane +1 more
TL;DR: Among the active substances released during anaphylaxis in guinea-pig lung is a hitherto unidentified substance which has a contracting effect on rabbit aorta.
The physiological action of β-iminazolylethylamine
H. H. Dale,P. P. Laidlaw +1 more
TL;DR: Ackermann and Kutscher as mentioned in this paper showed that the ergot base, though closely related to 8-iminazolylethylamine, is not identical with it.
Journal ArticleDOI
Early and late-phase bronchoconstriction after allergen challenge of nonanesthetized guinea pigs. I: The association of disordered airway physiology to leukocyte infiltration
TL;DR: A guinea pig model of asthma in which animals were sensitized and challenged by inhalation of aerosolized ovalbumin represents a useful animal model in which to study the mechanism of early and late bronchoconstriction responses.
Journal ArticleDOI
Antigen-induced bronchial anaphylaxis in actively sensitized guinea-pigs. Pattern of response in relation to immunization regimen.
TL;DR: Results show that guinea‐pigs sensitized with low amounts (1‐10μg) of ovalbumin together with alum produce the most pronounced bronchospasm when challenged with an intravenous injection of a low dose of antigen.
Journal ArticleDOI
Antagonism by Fenamates of Prostaglandin F 2α and of Slow Reacting Substance on Human Bronchial Muscle
TL;DR: It is explored how far meclofenamate and flufenamate antagonized the contraction of human isolated bronchial muscle induced by histamine, SRS-A or PGF2α.
References
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Journal ArticleDOI
The physiological action of β-iminazolylethylamine
H. H. Dale,P. P. Laidlaw +1 more
The physiological action of β-iminazolylethylamine
H. H. Dale,P. P. Laidlaw +1 more
TL;DR: Ackermann and Kutscher as mentioned in this paper showed that the ergot base, though closely related to 8-iminazolylethylamine, is not identical with it.
Journal ArticleDOI
Versuchsanordnung zu Untersuchungen an der Bronchiàlmuskulatur
Heribert Konzett,Richard Rössler +1 more
TL;DR: In this paper, Kiese et al. present a verwendung method for Registrierung physiologischer oder pharmakologischer' Wirkungen auf the Bronchialmuskulatur unter Erhaltung der natiirliehen Lungendurchblutung finden hauptsi~chlich zwei Methoden Verwendeungl: Das eine Veffahren beruht auf der Messung des Druekes in der Trachea bei gieichgehaltenem u
Journal ArticleDOI
The release of histamine and formation of a slow-reacting substance (SRS-A) during anaphylactic shock.
TL;DR: The experiments presented in the present paper show that in addition to the release of histamine, the antigen-antibody reaction results in the formation of another smooth muscle-stimulating substance which causes a slow and long-lasting contraction of the guinea-pig ileum, and which is resistant to anti-histamine drugs.
Journal ArticleDOI
The liberation of a slow-reacting smooth muscle-stimulating substance in anaphylaxis
C.E. Kellaway,E. R. Trethewie +1 more
TL;DR: It is concluded that the anaphylactic contraction of smooth muscles is in part due to the liberation of histamine and probably in part also to S.R.S., which is liberated and not formed in the antigenantibody reaction.
Related Papers (5)
Versuchsanordnung zu Untersuchungen an der Bronchiàlmuskulatur
Heribert Konzett,Richard Rössler +1 more
The release of histamine and formation of a slow-reacting substance (SRS-A) during anaphylactic shock.
Release of Additional Factors in Anaphylaxis and its Antagonism by Anti-inflammatory Drugs
Priscilla J. Piper,John R. Vane +1 more