Journal ArticleDOI
Hypercoagulability of the blood associated with ACTH and cortisone therapy.
TLDR
Changes have been observed in the venous clotting time and the heparin-retarded venous clots time which indicate that ACTH and cortisone frequently produce a hypercoagulable state of blood coagulation.About:
This article is published in The American Journal of Medicine.The article was published on 1950-12-01. It has received 150 citations till now. The article focuses on the topics: Clotting time & Cortisone.read more
Citations
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The heart in systemic lupus erythematosus and the changes induced in it by corticosteroid therapy: A study of 36 necropsy patients
TL;DR: Although vital to the management of SLE, corticosteroids have an over-all deleterious effect on the heart and systemic hypertension and left ventricular hypertrophy appear or, when present, worsen; congestive cardiac failure increases; epicardial apartment of Me.
Journal ArticleDOI
Clinical deterioration in patients with idiopathic pulmonary fibrosis: causes and assessment.
TL;DR: In evaluating clinical deterioration in patients with IPF, disease-associated complications and adverse effects of therapy should be distinguished from progressive pulmonary fibrosis.
Journal ArticleDOI
Corticosteroid therapy associated with ischemic necrosis of bone in systemic lupus erythematosus
TL;DR: In patients with ischemic necrosis of bone, there was a statistically significant correlation between higher mean prednisone dose at all time intervals and increased number of bony sites involved.
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The association of elevated plasma cortisol and early atherosclerosis as demonstrated by coronary angiography
TL;DR: Plasma cortisol was second only to serum cholesterol as a discriminator in the authors' patient population between diseased and non-diseased patients and a significant correlation between plasma cortisol and cholesterol, blood pressure, and smoking- the three cardinal risk factors for CAD.
References
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Journal ArticleDOI
A clinical study of the coagulation time of blood
Roger I. Lee,Paul D. White +1 more
Journal ArticleDOI
The nature of the bleeding in jaundice
TL;DR: Experimental observations made in studying the coagulation of blood are presented which furnish significant information on the nature of cholemic bleeding and to offer practical suggestions for the management of the jaundiced patient.
Journal Article
A protamine titration as an indication of a clotting defect in certain hemorrhagic states.
Allen Jg,Moulder Pv +1 more
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A study in intravascular thrombosis with some new conceptions of the mechanism of coagulation
Harold Cummine,Raymond N. Lyons +1 more
Journal ArticleDOI
Prothrombin Estimation A Procedure and Clinical Interpretations.
TL;DR: The procedure recommended is well suited for following the therapeutic effects of agents which influence the prothrombin level (or activity) such as dicumarol or vitamin K.