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Journal ArticleDOI

Hypophysectomy and a replacement therapy in the rat

Philip E. Smith
- 01 Mar 1930 - 
- Vol. 45, Iss: 2, pp 205-273
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This article is published in American Journal of Anatomy.The article was published on 1930-03-01. It has received 531 citations till now. The article focuses on the topics: Hypophysectomy.

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Citations
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Cell-Cell Interactions in the Testis

TL;DR: In conclusion, the information available indicates that the interactions between different cell types in the testis play an important role in the control and maintenance of testicular functions.
Journal ArticleDOI

The hormonal causes of premenstrual tension

TL;DR: My attention has been increasingly directed to a large group of women who are handicapped by premenstrual disturbances of manifold nature, in whom grave systemic disorders manifest themselves predominantly during the premen menstruation.
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Growth Hormone Stimulates Longitudinal Bone Growth Directly

TL;DR: This finding suggests that growth hormone directly stimulates the cells in the growth plate, and does not support the theory that the increase in the plasma concentration of somatomedin that follows growth hormone administration is the cause of this stimulation.
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The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight.

TL;DR: Lesion studies with weanling rats and adult pair-tube-fed rats, as well as recent studies of knockout mice deficient in the orphan nuclear receptor steroidogenic factor 1, indicate that VMH lesion-induced obesity is in large part a metabolic obesity (due to autonomic nervous system disorders) independent of hyperphagia.
Journal ArticleDOI

Effects of cortisone acetate and pituitary ACTH on rheumatoid arthritis, rheumatic fever and certain other conditions.

TL;DR: Cortisone is the hormone of the adrenal cortex previously known as compound E (17-hydroxy-11-dehydrocorticosterone) and ACTH is the pituitary adrenal corticotropic hormone which stimulates responsive adrenal glands to produce cortisone or a Cortisone-like steroid such as compound F as discussed by the authors.
References
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Journal ArticleDOI

The disabilities caused by hypophysectomy and their repair: the tuberal (hypothalamic) syndrome in the rat

Philip E. Smith
- 15 Jan 1927 - 
TL;DR: It is concluded that the hypophysis exercises few of the functions that have been attributed to it, and investigators have little actual knowledge of its functional significance in the adult animal.
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