Journal ArticleDOI
Immunochemotherapy of Bladder Carcinoma with Glucan and Cyclophosphamide
TLDR
Glucan, a derivative of the cell wall of Saccharomyces cerevisiae and a potent immunostimulant, was used in combination with cyclophosphamide for treatment of implanted murine transitional cell carcinoma.About:
This article is published in The American Journal of the Medical Sciences.The article was published on 1987-11-01. It has received 8 citations till now. The article focuses on the topics: Transitional cell carcinoma & Animal mortality.read more
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Preparation, characterization, and biological properties of β-glucans
TL;DR: The 4 M KOH fraction injected into rats with streptozotocin-induced diabetes has shown hypoglycemic activity, reducing blood sugar to normal levels for approximately 24 hours, better than that obtained with pure β-glucan from barley, which decreases blood sugar levels for about four hours.
Journal ArticleDOI
Fungal beta-glucan interacts with vitronectin and stimulates tumor necrosis factor alpha release from macrophages.
Eric J. Olson,Joseph E. Standing,Natalie Griego-Harper,Orleen A. Hoffman,Andandrew H. Limper +4 more
TL;DR: It is demonstrated that fungal beta-glucan can directly modulate TNF-alpha release from macrophages and that the host adhesive glycoprotein vitronectin specifically binds beta- glucan and augments macrophage cytokine release in response to this fungal element.
Journal ArticleDOI
Use of amaranth, quinoa and kañiwa in extruded corn-based snacks
Jose Martin Ramos Diaz,Satu Kirjoranta,Seppo Tenitz,Paavo A. Penttilä,Ritva Serimaa,Anna-Maija Lampi,Kirsi Jouppila +6 more
TL;DR: A co-rotating twin screw extruder was used to obtain corn-based extrudates containing amaranth/quinoa/kaniwa (20% of solids) as mentioned in this paper.
Biological effects of yeast β-glucans.
Vlatka Petravić-Tominac,Vesna Zechner-Krpan,Slobodan Grba,Siniša Srečec,Ines Panjkota-Krbavčić,Lana Vidović +5 more
TL;DR: β-Glucans work, in part, by stimulating the innate immune mechanism to fight a range of foreign challenges and could be used as an adjuvant, in combination with anti infective or antineoplastic agents, radiotherapy, and a rangeof topical agents and nutrients.
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Effects of spaceflight on polysaccharides of Saccharomyces cerevisiae cell wall
TL;DR: Genetic stability analysis showed that prolonged subculturing of spaceflight strain S. cerevisiae 2.0016 did not lead to the appearance of variants, indicating that the genetic stability of S. cerealvisiae could be sufficient for its exploitation of β-glucan production.
References
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Journal Article
Intravesical and Systemic Chemotherapy of Murine Bladder Cancer
TL;DR: It is hoped that information gained from these animal models, which allow evaluation of many drugs within a relatively short period of time, will identify drugs effective in transitional cell carcinoma and lead to therapeutic trials in patients with bladder cancer.
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Active immunotherapy with Corynebacterium parvum and chemotherapy in murine fibrosarcomas.
G. A. Currie,K. D. Bagshawe +1 more
TL;DR: Corynebacterium parvum used alone to enhance immunological reactivity produced transient inhibition of the growth of chemically induced isogenic mouse tumours and attempts were made to combine C. Parvum with cyclophosphamide to see whether this would increase the latter's effectiveness in inhibiting early but established tumours.
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The Molecular Constitution of an Insoluble Polysaccharide from Yeast, Saccharomyces cerevisiae
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Macrophage-Mediated Destruction of Human Malignant Cells In Vivo
TL;DR: Clinical studies were undertaken to enhance the recognition of malignant cells by macrophages and to mobilize and activate macrophage intralesionally and induced necrosis of the tumor nodule was associated with an increase in plasma levels of circulating RF activity.