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Journal ArticleDOI

Immunological aspects of homo- and heterologous bone marrow transplantation in irradiated animals.

D.W. van Bekkum, +1 more
- 01 Dec 1957 - 
- Vol. 50, pp 139-156
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This article is published in Journal of Cellular and Comparative Physiology.The article was published on 1957-12-01. It has received 79 citations till now. The article focuses on the topics: Heterologous.

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Citations
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Book

The Major Histocompatibility System in Man and Animals

TL;DR: One that the authors will refer to break the boredom in reading is choosing the major histocompatibility system in man and animals as the reading material.
Journal ArticleDOI

Autografts of bone marrow in dogs after lethal total-body radiation.

TL;DR: The working hypothesis is advanced that infusions of marrow repopulate marrow spaces in the canine after irradiation but are poor sources of the type of cell needed to restore lymphoid function and immunologic effectiveness in lymph nodes and spleen.
Book ChapterDOI

The Immunological Significance of the Thymus

TL;DR: This chapter discusses the effect of neonatal thymectomy in suppressing subsequent immunologic responsiveness and the extent to that immunologically competent cell originate in the thymus.
Journal ArticleDOI

"Secondary disease" of radiation chimeras: a syndrome due to lymphoid aplasia.

TL;DR: The “secondary disease” which afflicts mice after lethal irradiation and treatment with foreign bone marrow is now a well known phenomenon and evidence has accumulated suggesting that an immunological graft-versus-host reaction is involved in the pathogenesis of the syndrome.
Journal ArticleDOI

Preliminary observations on the treatment of postirradiation hematopoietic depression in man by the infusion of stored autogenous bone marrow

TL;DR: The work of Lorenz et al. on the protection of rodents against lethal x-radiation by the subsequent intravenous injection of bone marrow has been amply confirmed.
References
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Journal Article

Growth and Continued Function of Rat Marrow Cells in X-radiated Mice

TL;DR: The findings indicate that injected rat marrow cells survive, divide, and eventually repopulate the marrow cavity of irradiated mice, and suggests that transplanted rat marrow is actually functioning hematopoietically in the heterologous host.
Journal ArticleDOI

Mortality and skin transplantability in x-irradiated mice receiving isologous, homologous or heterologous bone marrow.

TL;DR: The degree and duration of protection afforded by isologous, homologous and heterologous sources of bone marrow administered after lethal doses of x-irradiation in mice was directly proportional to the closeness of genetic relationship of the marrow donor to the irradiated mice.
Journal Article

Evidence for a Humoral Factor (or Factors) Concerned in Recovery from Radiation Injury: A Review

Leon O. Jacobson
- 01 May 1952 - 
TL;DR: Prophylactic measures, such as pretreatment with estrogen or cysteine, have been used to reduce radiation morbidity and mortality in experimental animals, but, while of great mental importance, they are not effective in recovery when given after the radiation exposure has been sustained.
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