Impact of COVID-19 on Tuberculosis Case Detection and Treatment Outcomes in Sierra Leone.
Sulaiman Lakoh,Darlinda F. Jiba,Mamadu Baldeh,Olukemi Adekanmbi,Umu Barrie,Alhassan L. Seisay,Gibrilla F. Deen,Robert A. Salata,George A. Yendewa,George A. Yendewa,George A. Yendewa +10 more
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In this article, the authors conducted a retrospective study to assess the impact of the COVID-19 pandemic on TB case detection and treatment outcomes at the Chest Clinic at Connaught Hospital in Freetown, Sierra Leone.Abstract:
The COVID-19 pandemic has adversely affected tuberculosis (TB) care delivery in high burden countries. We therefore conducted a retrospective study to assess the impact of COVID-19 on TB case detection and treatment outcomes at the Chest Clinic at Connaught Hospital in Freetown, Sierra Leone. Overall, 2300 presumptive cases were tested during the first three quarters of 2020 (intra-COVID-19) versus 2636 in 2019 (baseline), representing a 12.7% decline. Testing declined by 25% in women, 20% in children and 81% in community-initiated referrals. Notwithstanding, laboratory-confirmed TB cases increased by 37.0% and treatment success rate was higher in 2020 (55.6% vs. 46.7%, p = 0.002). Multivariate logistic regression analysis found that age < 55 years (aOR 1.74, 95% CI (1.80, 2.56); p = 0.005), new diagnosis (aOR 1.69, 95% CI (1.16, 2.47); p = 0.007), pulmonary TB (aOR 3.17, 95% CI (1.67, 6.04); p < 0.001), HIV negative status (aOR 1.60, 95%CI (1.24, 2.06); p < 0.001) and self-administration of anti-TB drugs through monthly dispensing versus directly observed therapy (DOT) (aOR 1.56, 95% CI (1.21, 2.03); p = 0.001) independently predicted treatment success. These findings may have policy implications for DOTS in this setting and suggest that more resources are needed to reverse the negative impact of the COVID-19 pandemic on TB program activities in Sierra Leone.read more
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The impact of COVID-19 on communicable and non-communicable diseases in Africa: a narrative review.
Beatrice Formenti,Natalia Gregori,Verena Crosato,Valentina Marchese,Lina Rachele Tomasoni,Francesco Castelli +5 more
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Social and health factors associated with adverse treatment outcomes among people with multidrug-resistant tuberculosis in Sierra Leone: a national, retrospective cohort study
TL;DR: In this paper , the authors evaluated treatment outcomes among people with multidrug-resistant tuberculosis (MDR-TB) in Sierra Leone and investigated social and health factors associated with adverse treatment outcomes.
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An Intra-COVID-19 Assessment of Hand Hygiene Facility, Policy and Staff Compliance in Two Hospitals in Sierra Leone: Is There a Difference between Regional and Capital City Hospitals?
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TL;DR: In this paper, a cross-sectional study is aimed at assessing HH using the WHO HH self-assessment framework, HH technical reference manual, and a modified infection control selfassessment tool in two hospitals in Sierra Leone.
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How Well Are Hand Hygiene Practices and Promotion Implemented in Sierra Leone? A Cross-Sectional Study in 13 Public Hospitals
Sulaiman Lakoh,Anna Maruta,Christiana Kallon,Gibrilla F. Deen,James A. Russell,Bobson Derrick Fofanah,I. Kamara,Joseph Sam Kanu,Dauda M. Kamara,Bailah Molleh,Olukemi Adekanmbi,Simon Tavernor,Jamie A. Guth,Karuna D. Sagili,Ewan Wilkinson +14 more
TL;DR: Evaluating hand hygiene practices and promotion across public health hospitals in the Western Area of Sierra Leone in a cross-sectional study using the WHO hand hygiene self-Assessment framework in May 2021 found tertiary hospitals were poorly rated in the reminders in workplace and institutional safety climate domains but excelled in training and education.
References
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Improving the diagnostics of tuberculosis and drug resistance with Xpert MTB/RIF in a district general hospital in Sierra Leone: A quality improvement project
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