Journal ArticleDOI
Increased Whole Blood Viscosity on Cooling in a Patient with Cold Hemoagglutinin Disease
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TLDR
It is indicated that in cold hemoagglutinin disease, red cell aggregation and piling are capable of increasing blood viscosity.Abstract:
The whole blood and plasma viscosities have been evaluated in a patient with cold hemoagglutinin disease at different temperatures and at different shear rates. At 37 and 42 degrees C, whole blood viscosity values, regardless of the shear rate applied, resulted to be correspondent to the hematocrit value (31%). The values observed were similar to those noted in a patient with chronic bleeding anemia and an approximately equivalent hematocrit (33%). The same was true for plasma viscosity. At 32 degrees C, whole blood viscosity, regardless of the shear rate, resulted to be higher than expected. The values observed were similar to those noted in a normal subject with a clearly higher hematocrit value (44%) and definitely higher than those noted in the chronic anemia patient. On the contrary, plasma viscosity remained unchanged. These studies indicate that in cold hemoagglutinin disease, red cell aggregation and piling are capable of increasing blood viscosity.read more
Citations
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Journal ArticleDOI
B-Cell neoplasms with homogeneous cold-reacting antibodies (cold agglutinins)
David Crisp,Waldemar Pruzanski +1 more
TL;DR: Marked differences in the light chain type of cold agglutinins, specificity toward membranous antigens and severity of clinical manifestations were noted in benign and malignant varieties.
Journal ArticleDOI
Clinical syndromes associated with cold agglutinins.
TL;DR: Auto-immune haemolysis (AIHA) occurs when an individual's own red blood cells are destroyed by an autoantibody, and Anaemia ensues if bone marrow production of red cells cannot compensate for the increased loss ofred blood cells.
Journal Article
Cold blood and autoimmune hematologic disorders during cardiopulmonary bypass
TL;DR: Depistage, prevention and traitement concernant le syndrome d'agglutinines froides et l'hemoglobinurie paroxystique.
References
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Journal ArticleDOI
Abnormal rheology of oxygenated blood in sickle cell anemia
TL;DR: A role is assigned to the abnormal rheology of Hb SS erythrocytes in the pathogenesis of sickle cell anemia, even under conditions of complete oxygenation.
Journal ArticleDOI
Viscosity of normal human blood under normothermic and hypothermic conditions.
TL;DR: Although blood viscosity varies in relation to shear rate, hematocrit, and temperature, equipment is now available with which it may be measured in respect to each of these variables.
Journal ArticleDOI
Blood viscosity: influence of erythrocyte aggregation.
Shu Chien,Shunichi Usami,Robert J. Dellenback,Magnus I. Gregersen,Luddo B. Nanninga,M. Mason Guest +5 more
TL;DR: The data suggest that fibrinogen causes an increase in blood viscosity and a departure from Newtonian behavior by interacting with erythrocytes to form cell aggregates which can be dispersed by shear stress.
Journal ArticleDOI
Blood viscosity: influence of erythrocyte deformation.
TL;DR: In blood with high cell percentages, the shear deformation of normal RBC's plays an important role in reducing viscosity and facilitating flow at high shear stresses.
Journal ArticleDOI
Serum hyperviscosity syndrome.
TL;DR: The hyperviscosity syndrome commonly includes mucous membrane bleeding, retinopathy and loss of vision, and neurological disorders associated with elevated serum viscosity, and is frequently seen in patients with macroglobulinemia, with or without demonstrable lymphoma, but only rarely with multiple myeloma.
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