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Journal ArticleDOI

Intestinal failure-associated liver disease: what do we know today?

Deirdre Kelly
- 01 Feb 2006 - 
- Vol. 130, Iss: 2
TLDR
Management strategies for the prevention of intestinal failure-induced liver disease include early enteral feeding, a multidisciplinary approach to the management of parenteral nutrition, and aseptic catheter techniques to reduce sepsis.
About
This article is published in Gastroenterology.The article was published on 2006-02-01. It has received 323 citations till now. The article focuses on the topics: Parenteral nutrition & Cholestasis.

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Citations
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Journal ArticleDOI

ESPEN guidelines on chronic intestinal failure in adults

TL;DR: These GLs have been devised to generate comprehensive recommendations for safe and effective management of adult patients with CIF and require complex technologies, multidisciplinary and multiprofessional activity, and expertise to care for both the underlying gastrointestinal disease and to provide HPN support.
Journal ArticleDOI

ESPEN Guidelines on Parenteral Nutrition: home parenteral nutrition (HPN) in adult patients.

TL;DR: The purpose of these guidelines is to highlight areas of good practice and promote the use of standardized treatment protocols between centers, and may serve as a framework for development of policies and procedures.
Journal ArticleDOI

ESPEN guideline on clinical nutrition in liver disease.

TL;DR: This update of evidence-based guidelines (GL) aims to translate current evidence and expert opinion into recommendations for multidisciplinary teams responsible for the optimal nutritional and metabolic management of adult patients with liver disease.
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Identifying patients, on the first day of life, at high-risk of developing parenteral nutrition-associated liver disease

TL;DR: In the first days of life, certain NICU patients can be identified as being at very high risk for developing PNALD, and the highest direct bilirubin concentrations correlated with the highest serum alkaline phosphatase and transaminase concentrations.
Journal ArticleDOI

Incidence, Prevention, and Treatment of Parenteral Nutrition–Associated Cholestasis and Intestinal Failure–Associated Liver Disease in Infants and Children A Systematic Review

TL;DR: The incidence of PNAC/IFALD in children has no obvious decrease over time and high or intermediate-dose of oral erythromycin and aminoacid-free PN with enteral whey protein gained significant benefits in preterm neonates.
References
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Journal ArticleDOI

Prevalence of Liver Disease and Contributing Factors in Patients Receiving Home Parenteral Nutrition for Permanent Intestinal Failure

TL;DR: The natural history and prevalence of home parenteral nutrition-related liver disease and its prevalence and life-threatening complications have not been described, and the main postulated risk factors for home p Karenteral Nutrition- related liver disease have not be tested by using multivariate analysis.
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Nutritional and other postoperative management of neonates with short bowel syndrome correlates with clinical outcomes.

TL;DR: Although residual small bowel length remains an important predictor of duration of PN use in infants with SBS, other factors, such as use of breast milk or amino acid-based formula, may also play a role in intestinal adaptation.
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Does total parenteral nutrition induce gallbladder sludge formation and lithiasis

TL;DR: It is strongly suggested that bowel rest and bile stasis during parenteral nutrition lead to production of sludge, which can result in eventual gallstone formation and therefore, gallbladder stasis should be palliated to prevent cholelithiasis formation.
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The role of glutamine in maintaining a healthy gut and supporting the metabolic response to injury and infection

TL;DR: Critically ill patients are susceptible to developing gut-origin sepsis, the incidence of which will be diminished by instituting measures and providing treatments which support intestinal structure, function, and metabolism.
Journal ArticleDOI

Role of lipid emulsions in cholestasis associated with long-term parenteral nutrition in children.

TL;DR: The data suggest that lipid supply is one of the risk factors for PN-associated cholestasis, and the link between cholESTasis and the reticuloendothelial system overload needs to be better understood.
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