Journal ArticleDOI
Leukocyte ascorbic acid and its relationship to coronary artery disease in man
J Ramirez,N C Flowers +1 more
TLDR
It is suggested that ascorbic acid may play a role in the pathogenesis of atherosclerosis, and although not implicated as an etiological factor in coronary artery disease, it suggests that a closer look at its possible role inThe pathogenesis and progression of coronary arteries disease is warranted.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 1980-10-01. It has received 90 citations till now. The article focuses on the topics: Ascorbic acid & Coronary atherosclerosis.read more
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Antioxidants and Atherosclerotic Heart Disease
TL;DR: There is evidence that plaque stability, vasomotor function, and the tendency to thrombosis are subject to modification by specific antioxidants, and it is speculated that these mechanisms have an important role in the benefits of antioxidants.
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Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene
TL;DR: It is suggested that some populations with a high incidence of coronary heart disease may benefit from eating diets rich in natural antioxidants, particularly vitamin E.
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Antioxidant Vitamin Intake and Coronary Mortality in a Longitudinal Population Study
TL;DR: The hypothesis that antioxidant vitamins protect against coronary heart disease is supported, but it cannot be excluded that foods rich in these micronutrients also contain other constituents that provide the protection.
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A review of the epidemiological evidence for the 'antioxidant hypothesis'.
TL;DR: The suggestion that antioxidant supplements can prevent chronic diseases has not been proved or consistently supported by the findings of published intervention trials, and further evidence regarding the efficacy, safety and appropriate dosage of antioxidants in relation to chronic disease is needed.
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Criteria and recommendations for vitamin C intake.
TL;DR: The tolerable upper intake level, the highest daily level of nutrient intake that does not pose risk or adverse health effects to almost all individuals in the population, is proposed to be less than 1 g of vitamin C daily.