Lipolytic activity of some dermatophytes.
L. Hellgren,J. Vincent +1 more
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TLDR
Thelipolytic activities of four common dermatophytes, Epidermophyton floccosum, Microsporum canis, Trichophyton mentagrophytes and T. rubrum, were tested on agar medium supplemented with one or other of several lipids and the highest lipolytic activity was demonstrated by M. canis.Abstract:
THE HORNY layer of epidermis, which can be colonised by dermatophytes, is covered by surface lipids. The lipolytic activity of dermatophytes may therefore be of particular importance in the early stages of infection, before the fungus has established permanent contact with keratin; but little is known about the possible presence of lipases in these pathogenic fungi. The early observations of Mallinckrodt-Haupt (1927), Tate (1929), Nekam (1935) and, more recently, Pinetti and Lostia (1961) and Bohme (1969) have demonstrated that dermatophytes can hydrolyse lipids of animal and of vegetable origin. The occurrence of lipase has been demonstrated histochemically (Knight, 1957) and in dermatophyte mycelial filtrates (Bohme, 1969). This paper describes the screening of the more common dermatophytes to test for the presence of lipases.read more
Citations
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Current knowledge of host response in human tinea.
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Lipid Metabolism in Fungi
A Chopra,G K Khuller +1 more
TL;DR: The present review will bring out the differences or similarities of lipid metabolism in diverse fungal species and each section will deal, comparatively, with various aspects of fungal lipid metabolism and physiology.
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Phenotypic characterization of enzymatic activity of clinical dermatophyte isolates from animals with and without skin lesions and humans.
TL;DR: The aim of this study was to assess the capability of clinical dermatophyte isolates from both symptomatic and asymptomatic animals and humans to produce different enzymes.
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Human nail plate modifications induced by onychomycosis: implications for topical therapy.
Anna Maria Baraldi,Anna Maria Baraldi,Anna Maria Baraldi,Simon Jones,S. Guesné,M.J. Traynor,William J. McAuley,Marc B. Brown,Sudaxshina Murdan +8 more
TL;DR: Onchomycotic nails presented a thicker but more porous barrier, and its eroded intracellular matrix rendered the tissue more permeable to topically applied chemicals when an aqueous vehicle was used.
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Enzymatic and Non-Enzymatic Virulence Activities of Dermatophytes on Solid Media.
TL;DR: The virulence activity of phospholipase, lipase, protease and gelatinase was observed from all the dermatophyte species and the T. rubrum complex, T. mentagrophytes complex and A. grubyi showed complete haemolysis and hence they may also act as a non-enzymatic virulence marker for dermatophytes.
References
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TL;DR: This is the revision of the classic text in the field, adding two new chapters and thoroughly updating all others as discussed by the authors, and the original structure is retained, and the book continues to serve as a combined text/reference.
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TL;DR: The measurement of rank correlation was introduced in this paper, and rank correlation tied ranks tests of significance were applied to the problem of m ranking, and variate values were used to measure rank correlation.
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On the Enzymes of certain Dermatophytes, or Ringworm Fungi
TL;DR: In this paper, the enzymic activity of Dermatophyte fungi was studied in the following species: Sabouraudites radiolatus, S. lanosus; S. audouini; Trichophyton tonsurans; Grubyella schoenleinii.
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The Mechanism of Triglyceride Therapy in Dermatomycoses1
TL;DR: It is suggested that the superficial dermatophytes, serum, and cells of the skin could bring about the hydrolytic cleavage of glycerol esters, which would continue until the resulting low pH and the level of the products became inhibiting-an axiomatic proposition in enzymology.
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Mycelial suspensions prepared ultrasonically
TL;DR: Une méthode simple de préparation des suspensions mycéliales standardisées de dermatophytes a été établie dans des récipents munis de garde à coton.