Journal ArticleDOI
Long-term cognitive and neurological outcome of preterm infants with postnatally acquired CMV infection through breast milk
Rangmar Goelz,Christoph Meisner,Andrea Bevot,Klaus Hamprecht,Ingeborg Kraegeloh-Mann,Christian F. Poets +5 more
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TLDR
It seems possible that breast milk-acquired CMV infection has a detrimental influence on cognitive development of preterm infants with breast milk–acquired postnatalCMV infection.Abstract:
Introduction Long-term follow-up data on preterm infants with breast milk–acquired postnatal cytomegalovirus (CMV) infection are sparse. Aim To systematically evaluate the long-term cognitive outcome and prevalence of cerebral palsy (CP) in patients after postnatal CMV infection. Patients and methods All surviving infants 4 years. A blinded and controlled matched-pairs design was used with gestational age, gender and date of birth as matching criteria. Results Of 50 eligible children, 42 (84%) could be tested. There was no difference in the prevalence of cerebral palsy. Following CMV infection during their hospital stay, infants had significantly lower results in the simultaneous processing scale of the K-ABC (p=0.029) after correction for additional risk factors like socioeconomic status (SES). Results for the sequential and achievement scales were only slightly reduced (p>0.05). Conclusions It seems possible that breast milk-acquired CMV infection has a detrimental influence on cognitive development of preterm infants.read more
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Journal ArticleDOI
Blood Transfusion and Breast Milk Transmission of Cytomegalovirus in Very Low-Birth-Weight Infants A Prospective Cohort Study
Cassandra D. Josephson,Angela M. Caliendo,Kirk A. Easley,Andrea Knezevic,Neeta Shenvi,Michael Hinkes,Ravi Mangal Patel,Christopher D. Hillyer,John D. Roback +8 more
TL;DR: Transfusion of CMV-seronegative and leukoreduced blood products effectively prevents transmission ofCMV to VLBW infants, and among infants whose care is managed with this transfusion approach, maternal breast milk is the primary source of postnatal CMV infection.
Journal ArticleDOI
Microbial contamination of human milk purchased via the Internet.
Sarah A. Keim,Joseph S. Hogan,Kelly A. McNamara,Vishnu Gudimetla,Chelsea E. Dillon,Jesse J. Kwiek,Sheela R. Geraghty +6 more
TL;DR: Human milk purchased via the Internet exhibited high overall bacterial growth and frequent contamination with pathogenic bacteria, reflecting poor collection, storage, or shipping practices, and Infants consuming this milk are at risk for negative outcomes.
Journal ArticleDOI
Postnatal Cytomegalovirus Infection Through Human Milk in Preterm Infants: Transmission, Clinical Presentation, and Prevention.
Klaus Hamprecht,Rangmar Goelz +1 more
TL;DR: Short-term heat inactivation for 5 minutes at 62°C maintains the benefits of feeding BM without the disadvantages of CMV transmission; this can be applied effectively under routine conditions.
Journal ArticleDOI
Postnatal Human Cytomegalovirus Infection in Preterm Infants Has Long-Term Neuropsychological Sequelae
Katharina F. Brecht,Rangmar Goelz,Andrea Bevot,Ingeborg Krägeloh-Mann,Marko Wilke,Karen Lidzba +5 more
TL;DR: In this paper, the authors evaluated whether an early postnatal infection poses a long-term risk for neuropsychological impairment to neonates born very prematurely and found that adolescents born very preterm had significantly lower scores than term born controls on IQ (preterm: mean [SD] −98.43 [14.83], control: 110.00 [8.10], P ǫ=−.015) and on visuoperceptive abilities (95.64 [12.87] vs 106.24 [9.95] vs 102.75 [13
Journal ArticleDOI
Outcome of Preterm Infants With Postnatal Cytomegalovirus Infection
Julia Gunkel,Linda S. de Vries,Marian J. Jongmans,Corine Koopman-Esseboom,Ingrid C. van Haastert,Maria C.J. Eijsermans,Carolien van Stam,Bert G. A. van Zanten,Tom F.W. Wolfs,Joppe Nijman +9 more
TL;DR: In this cohort study, postnatal cytomegalovirus infection in preterm children did not have an adverse effect on neurodevelopment within the first 6 years of life.
References
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Breastfeeding and the use of human milk
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