Management of hepatic metastases
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TLDR
Management of hepatic metastases from neuroendocrine tumors and other noncolorectal primary tumors should be individualized based on the patient's clinical course, extent of disease, and symptoms.About:
This article is published in Liver Transplantation.The article was published on 1999-01-01 and is currently open access. It has received 81 citations till now. The article focuses on the topics: Neuroendocrine tumors & Sarcoma.read more
Citations
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Journal ArticleDOI
Guidelines for resection of colorectal cancer liver metastases
O. J. Garden,M Rees,Graeme J. Poston,Darius F. Mirza,Mark P Saunders,Jonathan A. Ledermann,John N. Primrose,Rowan W. Parks +7 more
TL;DR: There has been increasing recognition of the potential benefits of liver resection for colorectal metastases in the UK although this treatment has been established more widely in other Western countries and other new modalities have become available that allow safe ablation of liver metastases without the need for surgical intervention.
Journal ArticleDOI
Hepatic Metastasis from Colorectal Cancer.
Alan Isaac Valderrama-Treviño,Baltazar Barrera-Mera,Jesús Carlos Ceballos-Villalva,Eduardo E. Montalvo-Javé +3 more
TL;DR: It is very important to have knowledge of predisposing factors, diagnostic methods, and treatment of hepatic metastasis, and the establishment of newer, efficient, preventive screening programs for early diagnosis and adequate treatment is vital.
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Radio-frequency Ablation of Liver Tumors: Assessment of Therapeutic Response and Complications
Haesun Choi,Evelyne M. Loyer,Ronelle A. DuBrow,Harmeet Kaur,Cynthia L. David,Steven Y. Huang,Steven A. Curley,Chusilp Charnsangavej +7 more
TL;DR: Computed tomography (CT) is used most frequently to determine whether the ablation is complete and to screen for early recurrences that may benefit from reablation.
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Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells
Nathalie Scamuffa,Geraldine Siegfried,Yannick Bontemps,Liming Ma,Ajoy Basak,Ghislaine Cherel,Fabien Calvo,Nabil G. Seidah,Abdel-Majid Khatib +8 more
TL;DR: Inhibition of PCs in colon carcinoma cells in which PC activity was inhibited by overexpression of alpha1-PDX when injected into the portal vein of mice showed a significantly reduced ability to form liver metastases, suggesting that inhibition of PCs is a potentially promising strategy for the prevention of colorectal liver metastasis.
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Isolated hepatic perfusion for unresectable hepatic metastases from colorectal cancer
TL;DR: IHP can be performed with acceptably low morbidity and has significant antitumor activity in patients with unresectable hepatic metastases from colorectal cancer including those with refractory disease or PHR of 25 or greater.
References
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Cancer statistics, 1998
TL;DR: The Surveillance Research Program of the American Cancer Society's Department of Epidemiology and Surveillance reports its 32nd annual compilation of cancer incidence, mortality, and survival data for the United States and around the world.
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Liver resection for colorectal metastases.
Yuman Fong,Alfred M. Cohen,Joseph G. Fortner,Warren E. Enker,Alan D. Turnbull,Daniel G. Coit,A M Marrero,Mukesh Prasad,Leslie H. Blumgart,Murray F. Brennan +9 more
TL;DR: Liver resection for colorectal metastases is safe and effective therapy and currently represents the only potentially curative therapy for metastatic coloreCTal cancer.
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Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate by the advanced colorectal cancer meta-analysis project
Pascal Piedbois,Marc Buyse,Y. Rustum,D. Machover,C. Erlichman,Robert W. Carlson,F. Valone,R. Labianca,James H. Doroshow,N. Petrelli +9 more
TL;DR: Tumor response should not be considered a valid surrogate end point for survival in patients with advanced colorectal cancer in future trials, according to a meta-analysis performed on nine randomized clinical trials.
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Carcinoid Tumors An analysis of 2837 cases
TL;DR: Ccinoids showed several differences from other kinds of tumor, including a low age for appendiceal and lung cases and low male/female and black/white ratios in the lung.