Journal ArticleDOI
Measurement of bone mineral content in human vertebrae and hip by dual photon absorptiometry.
TLDR
An instrument for clinical measurement of bone mineral content in the axial skeleton was constructed and distinction of osteoporotic women from normal age-matched women was superior to that accomplished with single photon absorptiometry in the radius.Abstract:
An instrument for clinical measurement of bone mineral content in the axial skeleton was constructed. Components include a modified dual probe scanner, a PDP-11 computer, a 153Gd source, and a NaTI) detector. The results were accurate and highly reproducible, and distinction of osteoporotic women from normal age-matched women was superior to that accomplished with single photon absorptiometry in the radius.read more
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Journal ArticleDOI
Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis.
TL;DR: Bone mineral density was measured in vivo at the lumbar spine (predominantly trabecular bone) by dual photon absorptiometry and at the midradius (greater than 95% cortical bone) and distal radius (75% cortical and 25% trabECular bone), by single photon absorptioniometry as mentioned in this paper.
Journal ArticleDOI
Intermittent cyclical etidronate treatment of postmenopausal osteoporosis.
Nelson B. Watts,S. T. Harris,Harry K. Genant,Richard D. Wasnich,Paul D. Miller,Rebecca D. Jackson,A.A. Licata,Philip D. Ross,G C Woodson rd,M. J. Yanover +9 more
TL;DR: A prospective, two-year, double-blind, placebo-controlled, multicenter study in 429 women who had one to four vertebral compression fractures plus radiographic evidence of osteopenia to determine the effects of etidronate in the treatment of postmenopausal osteoporosis.
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Changes in Bone Mineral Density of the Proximal Femur and Spine with Aging: DIFFERENCES BETWEEN THE POSTMENOPAUSAL AND SENILE OSTEOPOROSIS SYNDROMES
B. L. Riggs,Heinz W. Wahner,Ego Seeman,Kenneth P. Offord,William L. Dunn,R. B. Mazess,K. A. Johnson,L. J. Melton +7 more
TL;DR: The data suggest the existence of two distinct syndromes: one form, "postmenopausal osteoporosis," is characterized by excessive and disproportionate trabecular bone loss, involves a small subset of women in the early postmenopausal period, and is associated with hip fractures or vertebral fractures or both.
Journal ArticleDOI
Reduced bone mass in daughters of women with osteoporosis.
Ego Seeman,John L. Hopper,Leon A. Bach,Mark E. Cooper,Elizabeth Parkinson,J. McKay,George Jerums +6 more
TL;DR: To determine whether premenopausal daughters of women with postmenopausal osteoporosis have lower bone mass than other women of the same age, the bone mineral content of the lumps were measured.
Journal ArticleDOI
Relative contributions of aging and estrogen deficiency to postmenopausal bone loss
TL;DR: It is suggested that estrogen deficiency, and not aging, may be the predominant cause of bone loss occurring during the first two decades after natural menopause.