Patent
Measurement of density and viscoelasticity with a single acoustic wave sensor
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TLDR
In this article, the authors used a piezoelectric device having at least two tightly coupled resonators providing a two pole electric transfer function responsive to an electrical signal coupled to the input resonator.Abstract:
A sensor, method and system, for measuring certain characteristics of a fluid. The sensor utilizes a piezoelectric device having at least two tightly coupled resonators providing a two pole electric transfer function responsive to an electrical signal coupled to the input resonator. The piezoelectric sensor has a textured entrapment layer, constructed to entrap a known volume of fluid and impart motion to the entrapped fluid as well as to surrounding non-trapped fluid. The common mode frequency shift of the two resonant frequencies is related to mass loading due to the entrapped fluid, while the energy absorbed by the fluid, or a phase shift of one of the resonant frequencies, is related to the viscosity/density product of the fluid. Extracting the viscosity is a matter of mathematical manipulation. By controlling the energy level of the input electrical signal, the viscosity measurement may be conducted at a predetermined shear rate.read more
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Patent
A density and viscosity sensor
Eric Donzier,Alfred Permuy +1 more
TL;DR: In this paper, a density and viscosity sensor is proposed to measure density and volumetric properties of fluid F using a resonating element 3, 3A, 3B, 3C, 3D arranged to be immersed in the fluid F and mechanically coupled to a membrane.
Patent
Manufacturing execution system for validation, quality and risk assessment and monitoring of pharmaceutical manufacturing processes
TL;DR: In this paper, the authors described and disclosed manufacturing execution systems relating to methods, systems, and software program for validation of pharmaceutical manufacturing processes and quality assurance process and provided a means to perform validation on an integrated level whereby the quality control unit can ensure data and product integrity and minimize cost.
Patent
Methods and apparatus for determining properties of a fluid
Eric Fitch,Stuart Wenzel +1 more
TL;DR: In this article, a method and system for determining properties of a fluid involves interacting the fluid with a standing wave in a first state to establish the standing wave by analyzing an electric signal associated with the standing waves to determine a characteristic associated with a second state, and determining the property of the fluid by comparing the characteristic with a function that associates a plurality of properties with a corresponding plurality of characteristics.
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Measurement of binding kinetics with a resonating sensor
TL;DR: In this paper, a subject material in a fluid sample is detected using a resonating sensor immersible in the fluid sample, and binding kinetics of an interaction of an analyte material present in the sample are measured with the resonating sensors.
Patent
Acoustic fluid analysis method
TL;DR: In this article, a smoothed first derivative with respect to time of the cumulative sum of squares (CSS) of the filtered amplitude data is determined, cross correlated to the time-shifted versions of itself.
References
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Patent
Method and system for detecting material using piezoelectric resonators
TL;DR: In this paper, a method and system for detecting material bound on a surface of a piezoelectric resonator is presented, where a multiple-port sensing device is provided which includes thin-film sensing and reference resonators monolithically formed on a substrate.
Patent
Monolithic piezoelectric sensor (MPS) for sensing chemical, biochemical and physical measurands
J.C. Andle,Ryszard M. Lec +1 more
TL;DR: A piezoelectric sensor and assembly for measuring chemical, biochemical and physical measurands is described in this article, which consists of a crystal, a common metal layer attached to the top surface of the piezo-lectric crystal, and a pair of independent resonators placed in close proximity on the crystal such that an efficacious portion of acoustic energy couples between the resonators.
Patent
Sensor array and method for determining the density and viscosity of a liquid
TL;DR: In this article, a sensor array for determining the density and viscosity of a liquid, comprising an array consisting of at least two basic sensor elements, at least one of which can be wetted with the liquid, in addition to electroacoustic converters disposed in the basic sensors for generating and detecting acoustic surface waves, is presented.
Patent
Textured-surface quartz resonator fluid density and viscosity monitor
Stephen J. Martin,James J. Wiczer,Richard W. Cernosek,Gregory C. Frye,Charles T. Gebert,Leonard Casaus,Mary A. Mitchell +6 more
TL;DR: In this paper, a pair of thickness-shear mode resonators, one smooth and one with a textured surface, allows fluid density and viscosity to be independently resolved, while the smooth device determines the density-viscosity product, and thus, the pair determines both density and viscosity.
Patent
Ultrasonic fluid densitometer having liquid/wedge and gas/wedge interfaces
TL;DR: In this paper, an ultrasonic liquid densitometer that uses a material wedge having two sections, one with a liquid/wedge interface and another with a gas/Wedge interface, is presented.