Metabolic differences in Angus steers divergently selected for residual feed intake

TLDR: It is hypothesised that high-RFI (low-efficiency) steers have higher tissue energy requirements, are more susceptible to stress and utilise different tissue substrates to generate energy required in response to exposure to a stressful stimulus.

Abstract: Residual feed intake measures variation in feed intake independent of liveweight and liveweight gain First generation steer progeny (n = 33) of parents previously selected for low or high post-weaning residual feed intake were examined to determine metabolic processes contributing to variation in residual feed intake Blood samples were taken from the steers from weaning through to slaughter These samples were analysed for key metabolites and hormones Total urine and total faecal collections were taken from the steers in an animal-house experiment to estimate dry matter digestibility, microbial protein production and protein turnover At weaning, there were phenotypic correlations between concentrations in plasma of β-hydroxy butyrate (r = 055, P 005) Neither the ratio of 3-methyl histidine : creatinine in urine, as a measure of rate of muscle breakdown, nor the dry matter digestibility measured in the animal house were correlated with residual feed intake in the animal house (r = 004, P>005), or residual feed intake over the whole experiment (r = –022, P>005), and neither were associated with genetic variation in residual feed intake It is hypothesised that high-RFI (low-efficiency) steers have higher tissue energy requirements, are more susceptible to stress and utilise different tissue substrates (partly as a consequence of differences in body composition) to generate energy required in response to exposure to a stressful stimulus