Journal ArticleDOI
Micromechanical analysis of bioresorbable PLLA/Mg composites coated with MgO: Effects of particle weight fraction, particle/matrix interface bonding strength and interphase
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TLDR
In this paper, the mechanical behavior of poly-lactic acid (PLLA) and magnesium (Mg) composite was characterized using a three-dimensional representative volume element (RVE) model and the influences of Mg weight fraction, imperfect bonding between particle and polymer matrix, and the interphase layer on the mechanical behaviors of the composites were quantified.Abstract:
Magnesium (Mg) particle has been recently introduced in a poly- l -lactic acid (PLLA) matrix to enhance to its mechanical properties. The coating of Mg particle could also regulate its degradation rate. In this work, the mechanical behavior of PLLA/Mg composite was characterized using a three-dimensional representative volume element (RVE) model. The influences of Mg weight fraction, imperfect bonding between particle and polymer matrix, and the interphase layer on the mechanical behaviors of the composites were quantified. Results clearly demonstrated that the effective Young's modulus and yield strength of the composite were enhanced by the Mg particles, as well as its MgO coating. In addition, the imperfect interfacial bonding between the Mg particle and PLLA weakened the mechanical advantage of the composite, which was in good agreement with the documented experimental observations. This work might shed some light on the optimal design and manufacturing of the bioresorbable composites.read more
Citations
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Stent Thrombogenicity Early in High Risk Interventional Settings is Driven by Stent Design and Deployment, and Protected by Polymer-Drug Coatings
Kumaran Kolandaivelu,Rajesh V. Swaminathan,William J. Gibson,Vijaya B. Kolachalama,Kim-Lien Nguyen-Ehrenreich,Virginia L. Giddings,Leslie Coleman,Gee K. Wong,Elazer R. Edelman +8 more
TL;DR: Optimal stent geometries and surfaces, as demonstrated with thin stent struts, help reduce the potential for thrombosis despite complex stent configurations and variability in deployment.
Journal ArticleDOI
Mechanical Characterizations of 3D-printed PLLA/Steel Particle Composites.
TL;DR: The results showed that the interphase layer provided a smooth transition of elastic modulus from steel particles to the polymeric matrix, and a 10% volume fraction of steel particles could enhance the elasticModulus of PLLA polymer by 31%.
Journal ArticleDOI
The design, fabrication and evaluation of 3D printed gHNTs/gMgO whiskers/PLLA composite scaffold with honeycomb microstructure for bone tissue engineering
Kun Liu,Wenyan Li,Shitian Chen,Wei Wen,Wei Wen,Lu Lu,Lu Lu,Mingxian Liu,Mingxian Liu,Changren Zhou,Changren Zhou,Binghong Luo,Binghong Luo +12 more
TL;DR: A novel 3D printing composite consumable consisting of poly ( l -lactide) matrix, surface grafted MgO whiskers and halloysite nanotubes (gHNTs) was developed, which can fully combine the printability of PLLA, the excellent osteogenic activity of gMgOs and the outstanding reinforcement and toughening effect of gH NTs.
Journal ArticleDOI
High efficient recovery of L-lactide with lignin-based filler by thermal degradation
TL;DR: In this paper, the effects of Lignin-graft-poly(D-lactic acid) (LG-g-PDLA) filler on PLLA pyrolysis were investigated.
Journal ArticleDOI
Microstructure, mechanical properties, and in-vitro biocompatibility of nano- NiTi reinforced Mg–3Zn-0.5Ag alloy: Prepared by mechanical alloying for implant applications
TL;DR: In this paper, the impacts of integrating 15, 30, and 45% of NiTi nano-particles on the characteristics of Mg-3Zn-0.5Ag magnesium alloy matrix have been investigated.
References
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Journal ArticleDOI
Average stress in matrix and average elastic energy of materials with misfitting inclusions
Trevor A. Mori,K Tanaka +1 more
TL;DR: In this paper, a method of calculating the average internal stress in the matrix of a material containing inclusions with transformation strain is presented. But the authors do not consider the effects of the interaction among the inclusions and of the presence of the free boundary.
Journal ArticleDOI
Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
Journal ArticleDOI
Intracoronary stenting and angiographic results: strut thickness effect on restenosis outcome (ISAR-STEREO-2) trial
Adnan Kastrati,Julinda Mehilli,Josef Dirschinger,Franz Dotzer,Helmut Schühlen,Franz-Josef Neumann,Martin Fleckenstein,Conrad Pfafferott,Melchior Seyfarth,Albert Schömig +9 more
TL;DR: When two stents with different design are compared, the stent with thinner struts elicits less angiographic and clinical restenosis than the thicker-strut stent.
Journal ArticleDOI
Stent Thrombogenicity Early in High-Risk Interventional Settings Is Driven by Stent Design and Deployment and Protected by Polymer-Drug Coatings
Kumaran Kolandaivelu,Rajesh V. Swaminathan,William J. Gibson,Vijaya B. Kolachalama,Kim-Lien Nguyen-Ehrenreich,Virginia L. Giddings,Leslie Coleman,Gee K. Wong,Elazer R. Edelman +8 more
TL;DR: This article examined whether drug-eluting coatings are inherently thrombogenic and if the response to these materials was determined to a greater degree by stent design and deployment with custom-built stents.
Stent Thrombogenicity Early in High Risk Interventional Settings is Driven by Stent Design and Deployment, and Protected by Polymer-Drug Coatings
Kumaran Kolandaivelu,Rajesh V. Swaminathan,William J. Gibson,Vijaya B. Kolachalama,Kim-Lien Nguyen-Ehrenreich,Virginia L. Giddings,Leslie Coleman,Gee K. Wong,Elazer R. Edelman +8 more
TL;DR: Optimal stent geometries and surfaces, as demonstrated with thin stent struts, help reduce the potential for thrombosis despite complex stent configurations and variability in deployment.