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Monoclonal antibodies in the diagnosis and treatment of malignant conditions.

W H Allum, +2 more
- 01 Jan 1986 - 
- Vol. 18, pp 41-64
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This article is published in Surgery.The article was published on 1986-01-01 and is currently open access. It has received 20 citations till now. The article focuses on the topics: Monoclonal antibody.

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Antibody conjugates reactive with human carcinomas

TL;DR: The BR96 antibody as mentioned in this paper is a single-chain immunotoxin that is reactive with a cell membrane antigen on the surface of human carcinoma cells and displays a high degree of selectivity for cancer cells and possess the ability to mediate antibodydependent cellular cytotoxicity and complement-dependent cytotoxin activity.
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Monoclonal antibody to novel antigen associated with human tumors

TL;DR: In this article, a monoclonal antibody which binds strongly to a protein antigen associated with human tumors, including carcinomas of the colon, breast, ovary and lung, as well as melanomas and sarcomas, was presented.
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Methods and compositions for diagnosing carcinomas

TL;DR: In this paper, the discovery of soluble forms of mesothelin polypeptides, including MRA, has been addressed, and a nucleic acid sequence encoding MRA and an MRA variant is provided.
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Antibodies reactive with human carcinomas

TL;DR: In this article, the authors describe a set of antibodies that are reactive with a cell membrane antigen on the surface of human carcinoma cells and possess the ability to mediate ADCC and CDC activity.
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Monoclonal antibody to human carcinomas

TL;DR: In this paper, a novel monoclonal antibody reactive with human carcinoma cells is presented. But the antibody is not suitable for use with other types of tumors such as lymphomas, sarcomas, or melanomas.
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