Mycotic keratitis: epidemiology, diagnosis and management
P.A. Thomas,J. Kaliamurthy +1 more
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TLDR
The PCR has gained prominence as a diagnostic aid for mycotic keratitis, being used to complement microbiological methods; more importantly, this molecular method permits rapid specific identification of the aetiological agent.About:
This article is published in Clinical Microbiology and Infection.The article was published on 2013-03-01 and is currently open access. It has received 342 citations till now. The article focuses on the topics: Fungal keratitis & Keratitis.read more
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Journal ArticleDOI
Recalcitrant Paecilomyces keratitis.
TL;DR: A 54-year-old Caucasian woman presented with corneal ulcer of the right eye of 4 weeks duration after scratching her cornea while removing her contact lens and artificial eye lashes, prompting reinitiation of ophthalmic and systemic antifungal agents.
Book ChapterDOI
Cellular and Molecular Basis of Ocular Diseases
TL;DR: In this paper , the cellular and molecular basis of several ocular diseases is discussed with respect to the role of accumulation of various cell types and various proteins and lipids that are either up- or downregulated in the diseased state of the eye.
Posted ContentDOI
Distribution, prevalence, and causative agents of fungal keratitis: A systematic review and meta-analysis (1990 to 2020)
Kazem Ahmadikia,S. Aghaei Gharehbolagh,Bahareh Fallah,M. Naeimi,Pooneh Malekifar,S. Rahsepar,Muhammad Ibrahim Getso,Savitri Sharma,Shahram Mahmoudi +8 more
TL;DR: A systematic review and meta-analysis as discussed by the authors collected all the articles with data on the prevalence of fungal keratitis among various patient groups from January 1, 1990 to May 27, 2020.
Journal ArticleDOI
Eye fungal infections: a mini review
Paula Reginatto,Rubia do Nascimento Fuentefria,Diane Ruschel Marinho,Melissa Manfroi Dal Pizzol,Alexandre Meneghello Fuentefria +4 more
TL;DR: In this paper , a search for scientific articles was conducted in databases, such as Medline, published from 2000 onwards, addressing important aspects involving fungal eye infections, highlighting the importance of constantly updating knowledge about these pathologies as it contributes to agility in choosing the available and most appropriate therapeutic alternatives, aiming at positive and minimally harmful results for that particular patient.
Journal ArticleDOI
Fungal Keratitis Treatment Using Drug-Loaded Hyaluronic Acid Microgels.
TL;DR: Antifungal drug-loaded hyaluronic acid (HA) microgels using conjugation and encapsulation drug-loading techniques were utilized in the treatment of fungal keratitis and showed no cytotoxicity on the L929 fibroblast cells up to 1000 μg/mL concentration, whereas the free drug molecules destroy the cells even at 100 μg/ mL concentration.
References
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Patent
Eye contact lens
TL;DR: In this paper, the end surface of an eye contact lens, having an outer front and rear surfaces, there are two patches lying in parallel on opposite sides of the lens, and on its front surface there is a film made from a selenium solution on which a protective coating made from methoxyethyl mercuric acetate is deposited.
Journal ArticleDOI
Taxonomy, biology, and clinical aspects of Fusarium species.
TL;DR: Foreign-body-associated fusarial infection such as keratitis in contact lens wearers, onychomycosis, skin infections, and disseminated multiorgan infections are discussed and the implications for the association of the carcinogens, fumonisins, produced by Fusarium moniliforme and other FUSarium species with human diseases are discussed.
Journal ArticleDOI
Current Perspectives on Ophthalmic Mycoses
TL;DR: Future research needs to focus on the development of rapid, species-specific diagnostic aids, broad-spectrum fungicidal compounds that are active by various routes, and therapeutic modalities which curtail the harmful effects of fungus- and host tissue-derived factors.
Journal ArticleDOI
Aetiology of suppurative corneal ulcers in Ghana and south India, and epidemiology of fungal keratitis.
A K Leck,Philip A. Thomas,M Hagan,J. Kaliamurthy,E Ackuaku,M John,Mercy J. Newman,F S Codjoe,Japheth A. Opintan,C.M. Kalavathy,V Essuman,C A N Jesudasan,G J Johnson +12 more
TL;DR: Infections of the cornea due to filamentous fungi are a frequent cause of corneal damage in developing countries in the tropics and are difficult to treat and microscopy is an essential tool in the diagnosis of these infections.
Journal ArticleDOI
The Changing Spectrum of Fungal Keratitis in South Florida
TL;DR: Trauma, including contact lens wear, is the most commonly associated risk factor, and the mainstay of therapy is topical natamycin with the increasing use of imidazoles.