Mycotic keratitis: epidemiology, diagnosis and management
P.A. Thomas,J. Kaliamurthy +1 more
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TLDR
The PCR has gained prominence as a diagnostic aid for mycotic keratitis, being used to complement microbiological methods; more importantly, this molecular method permits rapid specific identification of the aetiological agent.About:
This article is published in Clinical Microbiology and Infection.The article was published on 2013-03-01 and is currently open access. It has received 342 citations till now. The article focuses on the topics: Fungal keratitis & Keratitis.read more
Citations
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Journal ArticleDOI
The Utility of Repeat Culture in Fungal Corneal Ulcer Management: A Secondary Analysis of the MUTT-I Randomized Clinical Trial.
Kathryn J. Ray,Prajna Lalitha,N. Venkatesh Prajna,Revathi Rajaraman,Tiruvengada Krishnan,Muthiah Srinivasan,Peter Ryg,Stephen D. McLeod,Nisha R. Acharya,Thomas M. Lietman,Jennifer Rose-Nussbaumer +10 more
TL;DR: Early microbiological cure on culture is a predictor of clinical response to treatment in patients with smear-positive ulcers enrolled in MUTT-I.
Journal ArticleDOI
Epidemiological, clinical and laboratory findings of infectious keratitis at Mansoura Ophthalmic Center, Egypt.
TL;DR: Incidence of fungal keratitis is high in the authors' region and microbiological research should direct the antimicrobial treatment, according to the epidemiological, clinical and laboratory findings.
Journal ArticleDOI
Development of a Sustained-Release Voriconazole-Containing Thermogel for Subconjunctival Injection in Horses.
Rosemary Cuming,Eva Abarca,Eva Abarca,S. H. Duran,Anne A. Wooldridge,Allison J. Stewart,William R. Ravis,R. Jayachandra Babu,Yuh-Jing Lin,Terri Hathcock +9 more
TL;DR: In this article, the authors evaluated equine transcorneal and transscleral permeation of voriconazole (1.5% topical solution, 0.3% and 1.5%) for 24 hours.
Journal ArticleDOI
Distribution, Prevalence, and Causative Agents of Fungal Keratitis: A Systematic Review and Meta-Analysis (1990 to 2020)
Kazem Ahmadikia,Sanaz Aghaei Gharehbolagh,Bahareh Fallah,Mahsa Naeimi Eshkaleti,Pooneh Malekifar,Saeedeh Rahsepar,Muhammad Ibrahim Getso,Savitri Sharma,Shahram Mahmoudi +8 more
TL;DR: In this article, the authors provided an overview of the prevalence, distribution, and causative agents of fungal keratitis, and calculated the pooled estimated prevalence of mixed infections in general and in various countries using meta-analysis.
Journal ArticleDOI
Experimental Models for Fungal Keratitis: An Overview of Principles and Protocols
TL;DR: The key features of experimental models developed toward the development of better treatment options and key technical variations that could impact study design and outcomes are outlined.
References
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Patent
Eye contact lens
TL;DR: In this paper, the end surface of an eye contact lens, having an outer front and rear surfaces, there are two patches lying in parallel on opposite sides of the lens, and on its front surface there is a film made from a selenium solution on which a protective coating made from methoxyethyl mercuric acetate is deposited.
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Taxonomy, biology, and clinical aspects of Fusarium species.
TL;DR: Foreign-body-associated fusarial infection such as keratitis in contact lens wearers, onychomycosis, skin infections, and disseminated multiorgan infections are discussed and the implications for the association of the carcinogens, fumonisins, produced by Fusarium moniliforme and other FUSarium species with human diseases are discussed.
Journal ArticleDOI
Current Perspectives on Ophthalmic Mycoses
TL;DR: Future research needs to focus on the development of rapid, species-specific diagnostic aids, broad-spectrum fungicidal compounds that are active by various routes, and therapeutic modalities which curtail the harmful effects of fungus- and host tissue-derived factors.
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Aetiology of suppurative corneal ulcers in Ghana and south India, and epidemiology of fungal keratitis.
A K Leck,Philip A. Thomas,M Hagan,J. Kaliamurthy,E Ackuaku,M John,Mercy J. Newman,F S Codjoe,Japheth A. Opintan,C.M. Kalavathy,V Essuman,C A N Jesudasan,G J Johnson +12 more
TL;DR: Infections of the cornea due to filamentous fungi are a frequent cause of corneal damage in developing countries in the tropics and are difficult to treat and microscopy is an essential tool in the diagnosis of these infections.
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The Changing Spectrum of Fungal Keratitis in South Florida
TL;DR: Trauma, including contact lens wear, is the most commonly associated risk factor, and the mainstay of therapy is topical natamycin with the increasing use of imidazoles.