Nasal carriage of methicillin resistant Staphylococcus aureus among health care workers at a tertiary care hospital in Western Nepal
TLDR
High nasal carriage of S. aureus and MRSA among healthcare workers (especially in surgery ward and operating room) necessitates improved infection control measures to be employed to control MRSA transmission in this setting.Abstract:
Staphylococcus aureus is a frequent cause of infections in both the community and hospital. Methicillin-resistant Staphylococcus aureus continues to be an important nosocomial pathogen and infections are often difficult to manage due to its resistance to multiple antibiotics. Healthcare workers are important source of nosocomial transmission of MRSA. This study aimed to determine the nasal carriage rate of S. aureus and MRSA among healthcare workers at Universal College of Medical Sciences and Teaching Hospital, Nepal and to determine antibiotic susceptibility pattern of the isolates. A cross-sectional study involving 204 healthcare workers was conducted. Nasal swabs were collected and cultured on Mannitol salt agar. Mannitol fermenting colonies which were gram positive cocci, catalase positive and coagulase positive were identified as S. aureus. Antibiotic susceptibility test was performed by modified Kirby-Bauer disc diffusion method. Methicillin resistance was detected using cefoxitin disc diffusion method. Of 204 healthcare workers, 32 (15.7 %) were nasal carriers of S. aureus and among them 7 (21.9 %) were carrier of MRSA. Overall nasal carriage rate of MRSA was 3.4 % (7/204). Highest MRSA nasal carriage rate of 7.8 % (4/51) was found among nurses. Healthcare workers of both surgical wards and operating room accounted for 28.6 % (2/7) of MRSA carriers each. Among MRSA isolates inducible clindamycin resistance was observed in 66.7 % (2/3) of erythromycin resistant isolates. High nasal carriage of S. aureus and MRSA among healthcare workers (especially in surgery ward and operating room) necessitates improved infection control measures to be employed to control MRSA transmission in our setting.read more
Citations
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Streptomyces as a Prominent Resource of Future Anti-MRSA Drugs.
Hefa Mangzira Kemung,Loh Teng Hern Tan,Tahir Mehmood Khan,Tahir Mehmood Khan,Kok-Gan Chan,Priyia Pusparajah,Bey Hing Goh,Learn Han Lee +7 more
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TL;DR: The high rate of nasal MRSA carriage among healthcare workers found in this study is alarming and highlights the need for adjusted infection control measures to prevent MRSA transmission from HCWs to the vulnerable patient.
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Nasal carriage rate of methicillin resistant Staphylococcus aureus among Iranian healthcare workers: a systematic review and meta-analysis.
Mohammad Emaneini,Fereshteh Jabalameli,Hossein Ali Rahdar,Willem B. van Leeuwen,Reza Beigverdi +4 more
TL;DR: The rational use of antibiotics plus strict infection control are the main pillars for controlling multidrug resistant microorganisms such as MRSA in the hospital setting and these measurements should be applied nationally.
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Nasal Carriage Rate of Methicillin Resistant Staphylococcus aureus among Health Care Workers at a Tertiary Care Hospital in Kathmandu, Nepal.
Sabita Khatri,Narayan Dutt Pant,Raju Bhandari,Krishma Laxmi Shrestha,Chandrika Devi Shrestha,Nabaraj Adhikari,Asia Poudel +6 more
TL;DR: High rates of nasal carriage of S. a Aureus and Methicillin-resistant Staphylococcus aureus were observed among the healthcare workers, which indicate the need of strict infection control measures to be followed to control the nosocomial infections.
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Non-hospital environment contamination with Staphylococcus aureus and methicillin-resistant Staphylococcus aureus: proportion meta-analysis and features of antibiotic resistance and molecular genetics.
TL;DR: The results show that the risk from the MRSA strains was cross-transmitted among the population and it might be better to further identify the efficiency of the sterilization processes in a non-hospital environment so that relevant departments can take measures to improve disinfection of MRSA in non- hospital environments.
References
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TL;DR: The supplemental information presented in this document is intended for use with the antimicrobial susceptibility testing procedures published in the following Clinical and Laboratory Standards Institute (CLSI)–approved standards.
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TL;DR: The clinical and laboratory features of micro-organisms, including functions of blood, haematopoiesis and blood disorders, and their classification and features and classification are summarized.
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Changes in the Prevalence of Nasal Colonization with Staphylococcus aureus in the United States, 2001–2004
Rachel J. Gorwitz,Deanna Kruszon-Moran,Sigrid K. McAllister,Geraldine M. McQuillan,Linda K. McDougal,Gregory E. Fosheim,Bette Jensen,George Killgore,Fred C. Tenover,Matthew J. Kuehnert +9 more
TL;DR: Nal colonization with MRSA has increased in the United States, despite an overall decrease in nasal colonization with S. aureus, and PFGE types associated with community transmission only partially account for the increase.
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Health-care workers: source, vector, or victim of MRSA?
TL;DR: Both transiently and persistently colonised health-care workers were responsible for several MRSA clusters and subclinical infections and colonisation of extranasal sites were associated with persistent carriage.