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Neural mechanisms in life-threatening arrhythmias

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This article is published in American Heart Journal.The article was published on 1980-11-01. It has received 163 citations till now. The article focuses on the topics: Sympathectomy.

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Cardiovascular neural regulation explored in the frequency domain.

TL;DR: It is the opinion that rhythms and neural components always interact, just like flexor and extensor tones or excitatory and inhibitory cardiovascular reflexes, and that it is misleading to separately consider vagal and sympathetic modulations of heart rate.
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Heart Rate Variability: Measurement and Clinical Utility

TL;DR: Electrocardiographic RR intervals fluctuate cyclically, modulated by ventilation, baroreflexes, and other genetic and environmental factors that are mediated through the autonomic nervous system, and are useful for assessing risk of cardiovascular death or arrhythmic events, especially when combined with other tests.
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Heart Rate Variability as an Index of Sympathovagal Interaction After Acute Myocardial Infarction

TL;DR: Data indicate that the sympathetic predominance that is detectable 2 weeks after AMI is followed by recovery of vagal tone and a normalization of sympathovagal interaction, not only during resting conditions, but also in response to a sympathetic stimulus.
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Baroreflex sensitivity, clinical correlates, and cardiovascular mortality among patients with a first myocardial infarction. A prospective study.

TL;DR: BRS was assessed by calculating the regression line relating phenylephrine-induced increases in systolic blood pressure to the attendant changes in the RR interval and found that a reduced BRS primarily reflects an impairment in the vagal efferent component of the baroreceptor reflexes.
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QT interval prolongation predicts cardiovascular mortality in an apparently healthy population.

TL;DR: The results suggest that QT, contributes independently to cardiovascular risk, and it might be speculated that changes in life-style (e.g., with regard to physical exercise and smoking) may have a preventive impact.
References
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“Variant” angina: One aspect of a continuous spectrum of vasospastic myocardial ischemia: Pathogenetic Mechanisms, Estimated Incidence and Clinical and Coronary Arteriographic Findings in 138 Patients

TL;DR: Angiography in all 37 patients studied during angina revealed a severe coronary vasospasm involving vessels with extremely variable extent of atherosclerosis, which may evolve into acute myocardial infarction and sudden death.
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The long Q-T syndrome.

TL;DR: The possiblity for the correctly diagnosed and treated patients to escape an otherwise impending death calls urgently for diffusion of the knowledge about the long Q-T syndrome.
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Neural activity and ventricular fibrillation.

TL;DR: In this country, ventricular fibrillation is the likely mechanism for sudden death and the leading cause of fatality among patients with coronary heart disease.
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Functional distribution of right and left stellate innervation to the ventricles

TL;DR: The electrocardiographic form changes observed following unilateral alteration of sympathetic tone paralleled those electrocardsiographic abnormalities seen in patients with lesions of the central nervous system, suggesting a possible functional explanation for these clinical findings.
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Electrical alternation of the T-wave: Clinical and experimental evidence of its relationship with the sympathetic nervous system and with the long Q-T syndrome

TL;DR: These experiments provide further support on the relationships between the "long Q-T" syndrome and the sympathetic nervous system and indicate that alternation of the T-wave may depend on abrupt increases in the sympathetic discharge.
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