Journal ArticleDOI
Neuronal populations in the human brain.
TLDR
The ventral cochlear nucleus is studied because it is well defined and small enough to make accurate counts feasible and to study its role in deterioration of mental function in old age.Abstract:
THE deterioration of mental function in old age may be due to loss of neurones or decay of their function. Several studies support the former view1,2 but sample sizes and the number of cases reviewed were small. Accordingly we studied the ventral cochlear nucleus (VCN) because it is well defined and small enough to make accurate counts feasible.read more
Citations
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Journal ArticleDOI
Neuron numbers and dendritic extent in normal aging and Alzheimer's disease
Paul D. Coleman,Dorothy G. Flood +1 more
TL;DR: In this article, the authors reviewed evidence regarding neuron numbers and dendritic extent in normal aging rodent, monkey and human brain and in Alzheimer's disease and concluded that neuron loss and change in dendric extent are regionally specific, and corresponding brain regions do not always change in similar ways in rodents and primates.
Journal ArticleDOI
The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting.
TL;DR: A survey of original evidence shows that histological data always supported a 1:1 ratio of glia to neurons in the entire human brain, and a range of 40–130 billion glial cells, and the current status of knowledge about the number of cells is reviewed.
Journal ArticleDOI
Neocortical cell counts in normal human adult aging.
TL;DR: Aging affects the frontal and temporal lobes more than the parietal; the salient change is shrinkage of large neurons with consequently increasing numbers of small neurons in the midfrontal and superior temporal areas.
Journal ArticleDOI
The significance of the lewy body in the diagnosis of idiopathic parkinson's disease
W. R. G. Gibb,A. J. Lees +1 more
TL;DR: The significance of the Lewy body in the diagnosis of idiopathic Parkinson's disease is studied and its role in the treatment of the disease is investigated.
Journal ArticleDOI
Aging of the rat olfactory bulb: Growth and atrophy of constituent layers and changes in size and number of mitral cells
James W. Hinds,Nancy A. McNelly +1 more
TL;DR: A quantitative study of the rat olfactory bulb during aging was carried out by directly measuring or calculating the following parameters at 3, 12, 24, 27, and 30 months: the volume of the glomerular, external plexiform, and internal granular layers, a relative measure of the size of theOlfactory nerve layer, the mean volume of mitral cell nuclei and perikarya, and number of Mitral cells.
References
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Journal ArticleDOI
Organization of the cerebral cortex. III. A study of aging in the human cerebral cortex.
Journal ArticleDOI
Tables of Tolerance-Limit Factors for Normal Distributions
Alfred Weissberg,Glenn H. Beatty +1 more
TL;DR: In this article, a table of factors for use in computing two-sided tolerance limits is presented, where the factors r(N, P) and u(f, γ) whose product is equal to K are tabulated.