Patent
Noninvasive detection of rejection in heart transplant patients
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TLDR
In this paper, a method and apparatus for diagnosing heart rejection is disclosed. Heart rejection is diagnosed based on the pattern of interbeat intervals of the heart, which are measured shortly after transplant to establish a baseline pattern and compared to the baseline to detect changes from the baseline indicating rejection.Abstract:
A method and apparatus for diagnosing heart rejection is disclosed. Heart rejection is diagnosed based on the pattern of interbeat intervals. The interbeat intervals of the heart are measured shortly after transplant to establish a baseline pattern. The patterns of interbeat intervals from subsequent measurements are compared to the baseline to detect changes from the baseline indicating rejection. The apparatus of the invention measures the interbeat intervals using a Schmidt trigger that detects the upstroke of the QRS and produces a corresponding pulse. The intervals between pulses are timed to produce a series of interbeat interval measurements that are stored and analyzed. Software provides for automated pattern analysis.read more
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References
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A Real-Time QRS Detection Algorithm
Jiapu Pan,Willis J. Tompkins +1 more
TL;DR: A real-time algorithm that reliably recognizes QRS complexes based upon digital analyses of slope, amplitude, and width of ECG signals and automatically adjusts thresholds and parameters periodically to adapt to such ECG changes as QRS morphology and heart rate.
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Book
Chaos: Making a New Science
TL;DR: The chaos theory as mentioned in this paper is an extension of classical mechanics in which simple and complex causes are seen to interact, and the implications are staggeringly universal in all areas of scientific work and philosophical thought.
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Recurrence Plots of Dynamical Systems
TL;DR: In this article, a graphical tool for measuring the time constancy of dynamical systems is presented and illustrated with typical examples, and the tool can be used to measure the time complexity of a dynamical system.