Journal ArticleDOI
Novel surveillance and cure of a donor-transmitted lymphoma in a renal allograft recipient.
Karen A. Herzig,Michael C. Falk,Julie R. Jonsson,Roy A. Axelsen,A. Griffin,Carmel M. Hawley,Russell J. Rigby,Ralph Cobcroft,David Nicol,Elizabeth E. Powell,David W. Johnson +10 more
TLDR
Repeated surveillance of peripheral blood from both recipients, using a novel application of the technique of nested polymerase chain reaction to amplify donor DNA, demonstrated no persistence of donor cells, supporting effective eradication of the donor malignancy.Abstract:
Background. In this report we describe a malignant lymphoma of donor origin inadvertently transplanted into two renal allograft recipients, despite standard comprehensive donor screening, The successful clearance of the tumor from both patients and a novel method of surveillance are detailed.read more
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Journal ArticleDOI
Ovarian tissue and follicle transplantation as an option for fertility preservation.
Michael Grynberg,Marine Poulain,S. Sebag-Peyrelevade,Soizic le Parco,Renato Fanchin,Nelly Frydman +5 more
TL;DR: Although the clinical experience is limited, the robust results obtained open new perspectives for the management of premature ovarian failure resulting or not from gonadotoxic treatments.
Journal ArticleDOI
Influence of host-recipient origin on clinical aspects of posttransplantation lymphoproliferative disorders in kidney transplantation.
Barbara Petit,Yann Le Meur,Arnaud Jaccard,François Paraf,Claude Leroux Robert,Dominique Bordessoule,François Labrousse,Mireille Drouet +7 more
TL;DR: It is suggested that PTLD originating from the donor arise in the first year after transplantation into the graft, and that recipient-origin PTLD develop later as an invasive disease.
Journal ArticleDOI
Donor-transmitted cancer in kidney transplant recipients: a systematic review
Albino Eccher,Ilaria Girolami,Jennifer D. Motter,Stefano Marletta,Giovanni Gambaro,Rostand Emmanuel Nguefuet Momo,Francesco Nacchia,Paola Donato,Luigino Boschiero,Ugo Boggi,Letizia Lombardini,Massimo Cardillo,Antonietta D'Errico,D. Neil,Dorry L. Segev,Gianluigi Zaza +15 more
TL;DR: In this paper, the authors reviewed published case reports and series describing the outcome of recipients with donor-transmitted cancer until August 2019, and concluded that the most common transmitted cancers were lymphoma (n = 48, 20.5%), renal cancer (42, 17.9%), melanoma and lung cancer had the worst prognosis, with 5-years overall survival of 43% and 19%, respectively; while renal cell cancer and lymphomas had a favorable prognosis with 93 and 63%, respectively.
Journal ArticleDOI
Autotransplantation of cryopreserved ovarian tissue: a procedure with promise, risks, and a need for a registry.
Lisa A. Kolp,Ziad R. Hubayter +1 more
TL;DR: The ability to efficiently and safely preserve the reproductive potential of thousands of young female cancer patients looks possible, but many issues are not yet resolved.
Journal ArticleDOI
Donor-related malignancies
H. Myron Kauffman,Maureen A. McBride,Wida S. Cherikh,Pamela C Spain,Douglas W. Hanto,Francis L. Delmonico +5 more
TL;DR: Reports of and problems with specific donor-related tumors such as malignant melanoma, choriocarcinoma, primary central nervous systemmalignancies, renal tumors, carcinoma of the lung, Kaposi's sarcoma, and hematologic and lymphomatous malignancies are detailed.