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Journal ArticleDOI

Nutraceutical management of metabolic syndrome as a palliative and a therapeutic to coronavirus disease (COVID) crisis.

TLDR
A review on the biological activities of some plant products used as complementary and alternative medicines in the management of metabolic syndromes, and on their reported antiviral, antithrombotic, angiotensin-converting enzyme inhibitory properties, which are integral to their usage in management of viral infections and may give an avenue for prophylactic and therapeutics especially in the absence of vaccines/formulated antiviral therapies as mentioned in this paper.
Abstract
The global market for medicinal plants and herbs is on the increase due to their desirability, efficacy, and less adverse effects as complementary and alternative medications to the orthodox pharmaceuticals, perhaps due to their natural components and qualities. Metabolic syndromes are managed with changes in diet, exercise, lifestyle modifications and the use of pharmacological agents. Plants are now known to have potent antioxidant and cholinergic activities which are relevant to the management of several metabolic syndromes, which are unfortunately, co-morbidity factors in the coronavirus disease crisis. This review will focus on the biological activities of some plant products used as complementary and alternative medicines in the management of metabolic syndromes, and on their reported antiviral, antithrombotic, angiotensin-converting enzyme inhibitory properties, which are integral to their usage in the management of viral infections and may give an avenue for prophylactic and therapeutics especially in the absence of vaccines/formulated antiviral therapies.

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Citations
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Journal ArticleDOI

Cross-National Variations in COVID-19 Mortality: The Role of Diet, Obesity and Depression

TL;DR: In this article, the authors examined the relationship between the prevalence of depression and obesity and per capita consumption of sugar and seafood, and country-wise prevalence of obesity and depression in the COVID-19 pandemic.
Journal ArticleDOI

Luteolin and Vernodalol as Bioactive Compounds of Leaf and Root Vernonia amygdalina Extracts: Effects on α-Glucosidase, Glycation, ROS, Cell Viability, and In Silico ADMET Parameters

TL;DR: In this article , the amount of luteolin and vernodalol in leaf and root extracts was detected, and their role was studied regarding α-glucosidase activity, bovine serum albumin glycation (BSA), reactive oxygen species (ROS) formation, and cell viability, together with in silico absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties.
References
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Journal ArticleDOI

The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis.

TL;DR: A systematic review and meta-analysis of the cardiovascular risk associated with the metabolic syndrome as defined by the 2001 NCEP and 2004 revised National Cholesterol Education Program definitions found the syndrome is associated with a 2-fold increase in cardiovascular outcomes and a 1.5- fold increase in all-cause mortality.
Journal ArticleDOI

Metabolic Syndrome and Risk of Incident Cardiovascular Events and Death: A Systematic Review and Meta-Analysis of Longitudinal Studies

TL;DR: The best available evidence suggests that people with MetSyn are at increased risk of cardiovascular events and should fuel research of other preventive interventions.
Journal ArticleDOI

Antimicrobial properties of allicin from garlic.

TL;DR: The main antimicrobial effect of allicin is due to its chemical reaction with thiol groups of various enzymes, e.g. alcohol dehydrogenase, thioredoxin reductase, and RNA polymerase, which can affect essential metabolism of cysteine proteinase activity involved in the virulence of E. histolytica.
Journal ArticleDOI

Safety and Anti-Inflammatory Activity of Curcumin: A Component of Tumeric (Curcuma longa)

TL;DR: Curcumin has been demonstrated to be safe in six human trials and has demonstrated anti- inflammation activity and may exert its anti-inflammatory activity by inhibition of a number of different molecules that play a role in inflammation.
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