Journal ArticleDOI
Osteogenic protein-1 stimulates proliferation and differentiation of human bone cells in vitro.
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TLDR
The results suggest that OP-1 could be an important regulator of osteoblast proliferation and differentiation and modulates the effects of 1,25(OH)2D3 on ALP activity.About:
This article is published in Biochemical and Biophysical Research Communications.The article was published on 1993-08-16. It has received 85 citations till now. The article focuses on the topics: Osteoblast & Alkaline phosphatase.read more
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The Concept of Induced Membrane for Reconstruction of Long Bone Defects
Alain C. Masquelet,Thierry Bégué +1 more
TL;DR: The induced membrane appears as a biological chamber, which allows the conception of numerous experimental models of bone reconstruction and could probably be extended to other tissue repair.
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Bone morphogenetic proteins in human bone regeneration.
E.H.J. Groeneveld,E.H. Burger +1 more
TL;DR: Animal studies and laboratory experiments reveal a number of conditions that influence the osteoinductivity of BMP, such as BMP concentration, carrier properties and influence of local and systemic growth factors and hormones.
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Growth factors for bone growth and repair: IGF, TGFβ and BMP
TL;DR: In vivo studies are discussed which demonstrate the applicability of IGFs, TGF betas and BMPs to increasing bone formation systemically, promoting fracture healing and inducing bone growth around implants.
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Growth factors to stimulate bone formation
TL;DR: It is proposed that different growth factors may have a specific role in regulating proliferation and differentiation of different stages of osteoblast lineage cells and play important roles in the local regulation of bone formation.
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Divide, accumulate, differentiate : cell condensation in skeletal development revisited
Brian K. Hall,Tsutomu Miyake +1 more
TL;DR: Three major phases of chondrogenesis are identified: (a) epithelial-mesenchymal interactions that precede condensation, (b) condensation itself, and (c) cell differentiation.