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Pandemic Preparedness: Maintaining Adequate Immune Fitness by Attaining a Normal, Healthy Body Weight

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TLDR
Attaining a normal, healthy body weight might be an essential component of pandemic preparedness and should be supported by creating awareness and promoting the importance of regular exercise and the consumption of healthy food.
Abstract
In addition to developing effective medicines and vaccines, pandemic preparedness also comprises general health-related, behavioral, and psychological aspects related to being more resistant in the case of future pandemics. In the context of the 2019 coronavirus (COVID-19) pandemic, recent research revealed that reduced perceived immune fitness was the best predictor of reporting more frequent and more severe COVID-19 symptoms. Up until now (June 2022), during the COVID-19 pandemic, the majority of patients who have been hospitalized were characterized as being overweight. It is therefore essential to further evaluate the relationship between body mass index (BMI) and immune fitness. This was performed by analyzing pooled data from previously published studies, conducted among N = 8586 Dutch adults. It was hypothesized that attaining a normal, healthy body weight is associated with optimal perceived immune fitness. The analysis revealed that a deviation from normal weight (i.e., having a BMI outside the range of 18.5 to 24.9 kg/m2) was associated with significantly reduced perceived immune fitness, as assessed with the immune status questionnaire and a single item perceived immune fitness scale. The effects were significant for both underweight and overweight groups and most pronounced for the obese groups. The results suggest that attaining a normal, healthy body weight might significantly contribute to maintaining adequate perceived immune fitness. Therefore, attaining a normal body weight might be an essential component of pandemic preparedness and should be supported by creating awareness and promoting the importance of regular exercise and the consumption of healthy food.

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Journal ArticleDOI

The Assessment of Immune Fitness

TL;DR: In this article , a single-item rating scale was used to assess immune fitness and the scale can be used in conjunction with a single "yes" or "no" question asking whether the individual is experiencing reduced immune fitness.
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COVID-19 Lockdown Effects on Mood, Alcohol Consumption, Academic Functioning, and Perceived Immune Fitness: Data from Young Adults in Germany

TL;DR: Overall, a reduction in alcohol consumption during lockdown periods was shown, and academic functioning in terms of self-reported performance was unaffected, however, a significant reduction in interactions with other students and teachers was reported.
Journal ArticleDOI

Reduced Immune Fitness and Job Performance: Absenteeism, Presenteeism, and Associated Costs for the Dutch Economy

TL;DR: In this article , the authors evaluated the impact of reduced immune fitness on job performance and associated costs for the Dutch economy, and showed that reduced immunity can have a significant negative impact on work performance.
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Pandemic Preparedness: The Potential Advantage of Medicines That Prevent Acute Side Effects of Vaccination, SARS-CoV-2 as an Example

TL;DR: The importance of recognizing the impact of this reactogenicity on individuals’ willingness to vaccinate and how the development of effective and safe medicines that prevent or mitigate the unwanted side effects of the vaccination may help to increase the willingness tovaccinate is discussed.
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An evening of alcohol consumption negatively impacts next-day immune fitness in both hangover-sensitive drinkers and hangover-resistant drinkers.

TL;DR: In this article , the authors assess immune fitness and saliva biomarkers of systemic inflammation at multiple timepoints following an alcohol day and alcohol-free control day, and find that the reduction in immune fitness was significantly more pronounced in the hangover-sensitive group compared to the non-hangover group.
References
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Journal ArticleDOI

Obesity and overweight

TL;DR: This data shows that 42 million children under the age of 5 were overweight or obese in 2013, and 65% of the world's population live in countries where overweight and obesity kills more people than underweight.
Journal ArticleDOI

Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study.

TL;DR: Age and comorbidities were found to be strong predictors of hospital admission and to a lesser extent of critical illness and mortality in people with coronavirus disease 2019 in the United States; however, impairment of oxygen on admission and markers of inflammation were most strongly associated with critical illnesses and mortality.
Journal ArticleDOI

Indices of relative weight and obesity

TL;DR: The body mass index seems preferable over other indices of relative weight on these grounds as well as on the simplicity of the calculation and, in contrast to percentage of average weight, the applicability to all populations at all times.
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What are the health behaviors that can increase body resistance in facing the COVID pandemic?

The paper mentions that mental health (e.g., stress reduction), healthy nutrition, and regular physical activity can directly improve immune fitness and contribute to pandemic preparedness.