Patent
Pharmaceutical composition containing 4-oxo-butynic acids
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TLDR
In this article, a pharmaceutical composition containing, as active principle, a compound of formula (a) in which groups A and B are selected independently of each other among: a monocyclic, bi-cyclic or tricyclic aryl group having 6 to 14 carbon atoms; a heteroaraomatic group selected among the pyridyl, pyrimidyl and pyrrolyl, furyl and thienyl groups.Abstract:
The invention concerns a pharmaceutical composition containing, as active principle, a compound of formula (a) in which groups A and B are selected independently of each other among: a mono-cyclic, bi-cyclic or tri-cyclic aryl group having 6 to 14 carbon atoms; a heteroaraomatic group selected among the pyridyl, pyrimidyl, pyrrolyl, furyl and thienyl groups; an alkyl group having 1 to 14 carbon atoms; a cycloalkyl group having 5 to 8 carbon atoms; a saturated heterocyclic group selected among the tetrahydrofuryl, tetrahydropyrranyl, piperidinyl and pyrrolidinyl groups; its solvate or a salt of this acid with a pharmaceutically acceptable base.read more
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Pharmaceutical composition comprising a combination of metformin and a 4-oxobutanoic acid, and the use thereof for treating diabetes
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N-morpholino derivatives and their use as anti-hypertensive agents
Harold N. Weller,Denis E. Ryono +1 more
TL;DR: In this article, compounds of the formula ''STR1'' are disclosed. These compounds are inhibitors of renin and therefore useful as cardiovascular agents. But they are not suitable for use in medical applications.
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Peptide-like aminoacid derivatives
TL;DR: In this paper, the meaning of the formula in which R, R, R, A, R and A have the meaning given in Claim 1, and pharmaceutically utilisable salts thereof have renin-inhibiting properties and can therefore be used in the form of pharmaceutical preparations as medicaments.
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Derives d'alcools n-heterocycliques a action therapeutique
Harold N. Weller,Denis E. Ryono +1 more
TL;DR: In this article, the formule :X-CH2 -CH-C-NH-CH-CCN-CHC-R1 -C-N-NH, CH-CNCN-CNH, C-NHN, CHCH-CHR1, CH-RCCN,CH-RNCN.