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Journal ArticleDOI

Physiology and pathobiology of axons

Stephen G. Waxman, +1 more
- 01 Feb 1979 - 
- Vol. 50, Iss: 2, pp 179-179
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This article is published in Anesthesiology.The article was published on 1979-02-01. It has received 216 citations till now. The article focuses on the topics: Axon.

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Neuregulin-1 type III determines the ensheathment fate of axons.

TL;DR: Levels of NRG1 type III, independent of axon diameter, provide a key instructive signal that determines the ensheathment fate of axons, indicating that axons are ensheathed or myelinated by Schwann cells.
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CNS Myelin and Sertoli Cell Tight Junction Strands Are Absent in Osp/Claudin-11 Null Mice

TL;DR: It is demonstrated that OSP is the mediator of parallel-array tight junction strands and distinguishes this protein from other intrinsic membrane proteins in tight junctions, providing direct evidence of the pivotal role of the claudin family in generating the paracellular physical barrier of tight junications necessary for spermatogenesis and normal CNS function.
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Polyneuropathy in critically ill patients

TL;DR: The electrophysiological and morphological features indicate a primary axonal polyneuropathy with sparing of the central nervous system, which allow diagnosis during life, and encourage continued intensive management since recovery from the polyne neuropathy may occur.
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Calcium-binding protein parvalbumin as a neuronal marker

TL;DR: The localization by immunohistological means of parvalbumin in neurones scattered throughout the central nervous system of the rat is described and the physiological function of parValbumin-immunoreactive neurones is described.
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The acoustic startle reflex: neurons and connections.

TL;DR: The startle reflex protects animals from blows or predatory attacks by quickly stiffening the limbs, body wall and dorsal neck in the brief time period before directed evasive or defensive action can be performed.