Journal ArticleDOI
Physiopathological effects of rapeseed oil: a review.
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TLDR
Rapeseed oil has a growth retarding effect in animals and erucic acid lowers the respiratory capacity of the heart mitochondria and the lifespan of rats is the same on corn oil, soybean oil, coconut oil, whale oil and rapeseed oil diet.Abstract:
Rapeseed oil has a growth retarding effect in animals. Some investigators claim that the high content of erucic acid in rapeseed oil alone causes this effect, while others consider the low ratio saturated/monounsaturated fatty acids in rapeseed oil to be a contributory factor. Normally erucic acid is not found or occurs in traces in body fat, but when the diet contains rapeseed oil erucic acid is found in depot fat, organ fat and milk fat. Erucic acid is metabolized in vivo to oleic acid. The effects of rapeseed oil on reproduction and adrenals, testes, ovaries, liver, spleen, kidneys, blood, heart and skeletal muscles have been investigated. Fatty infiltration in the heart muscle cells has been observed in the species investigated. In long-term experiments in rats erucic acid produces fibrosis of the myocardium. Erucic acid lowers the respiratory capacity of the heart mitochondria. The reduction of respiratory capacity is roughly proportional to the content of erucic acid in the diet, and diminishes on continued administration of erucic acid. The lifespan of rats is the same on corn oil, soybean oil, coconut oil, whale oil and rapeseed oil diet. Rats fed a diet with erucic acid or other docosenoic acids showed a lowered tolerance to cold stress (+4 degrees C). In Sweden erucic acid constituted 3-4% of the average intake of calories up to 1970 compared with about 0.4% at present.read more
Citations
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Journal ArticleDOI
Cardiolipin and apoptosis.
TL;DR: Potential regulatory mechanisms in CL synthesis and the effects of de-acylation pathways on steady state levels of CL and its interaction with cytochrome c are described and the model of fatty acid induced apoptosis is used as a paradigm to understanding of the temporal relationship between decreased mitochondrial CL, release of cy tochrome c, and initiation of apoptosis.
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Detection and identification of extra virgin olive oil adulteration by GC-MS combined with chemometrics.
TL;DR: In this study, an analytical method for the detection and identification of extra virgin olive oil adulteration with four types of oils (corn, peanut, rapeseed, and sunflower oils) was proposed and demonstrated that higher contents of eicosanoic acid, docosanoim acid, tetracosanoIC acid, and SFAs were the peculiarities of peanut adulterations.
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Pigs fed camelina meal increase hepatic gene expression of cytochrome 8b1, aldehyde dehydrogenase, and thiosulfate transferase
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References
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Journal ArticleDOI
Pathological effects of dietary rapeseed oil in rats.
A.M.M. Abdellatif,R.O. Vles +1 more
TL;DR: It was shown that the fatty infiltration of the heart and skeletal muscles occurs after 1 day of RSO feeding and becomes most severe after 3–6 days, and erucic acid appears to be the constituent in RSO responsible for its pathological effects.
Journal ArticleDOI
Cardiac Lipid Changes in Rats Fed Oils Containing Long-Chain Fatty Acids
TL;DR: In this paper, the composition of the cardiac fatty acids and the histopathology in rats receiving oil as 40% of calories were studied after 3, 7, 14 and 28 days.
Journal ArticleDOI
Histopathological changes in rats and pigs fed rapeseed oil
TL;DR: The pigs appeared to be in general more sensitive than rats to the high fat content of the diet, for all the examined pigs showed histological evidence of thyroid hyperfunction, interstitial myocarditis, and inflammatory reaction in the gastric mucosa.
Journal ArticleDOI
Cardiac lipids in rats and gerbils fed oils containing C 22 fatty acids.
TL;DR: Oil fromLimnanthes douglasii and hydrogenated herring oil also increased the amount of cardiac fatty acids in gerbils, and a high intake of docosenoic acid was common to the animals displaying the cardiac alterations.