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Open AccessJournal ArticleDOI

Plasma natriuretic peptide levels increase with symptoms and severity of mitral regurgitation.

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TLDR
Ass associations between plasma natriuretic peptide levels and the severity and symptoms of mitral regurgitation (MR) and are higher in symptomatic compared to asymptomatic patients, even when LV EF is normal are described.
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This article is published in Journal of the American College of Cardiology.The article was published on 2003-06-18 and is currently open access. It has received 200 citations till now. The article focuses on the topics: Natriuretic peptide & Brain natriuretic peptide.

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Citations
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2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

TL;DR: The reader is referred to the full guideline for graphical flow charts, text, and tables with additional details about the rationale for and implementation of each recommendation, and the evidence tables detailing the data considered in developing these guidelines.
Journal ArticleDOI

2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary

TL;DR: The reader is referred to the full guideline for graphical flow charts, text, and tables with additional details about the rationale for and implementation of each recommendation, and the evidence tables detailing the data considered in developing these guidelines.
References
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Journal ArticleDOI

Radioimmunoassay and characterization of atrial natriuretic peptide in human plasma.

TL;DR: Plasma immunoreactive ANP is responsive to sodium loading in normal man and is elevated in patients with hypervolemic disorders, indicating that the heart secretes alpha hANP or a closely similar peptide which is also present in peripheral venous plasma.
Journal ArticleDOI

Left ventricular function after valve repair for chronic mitral regurgitation: Predictive value of preoperative assessment of contractile reserve by exercise echocardiography

TL;DR: In minimally symptomatic patients with mitral regurgitation, latent ventricular dysfunction may be indicated by a limited contractile reserve, manifest at exercise as an inadequate increase in ejection fraction and a larger end-systolic volume.
Journal ArticleDOI

Plasma A- and B-type natriuretic peptides: physiology, methodology and clinical use

TL;DR: Under pathological conditions production of BNP rises strongly in both atria and ventricles and plasma concentrations may overtake those of (also risen) ANP, while both are formed as pre-pro-polypeptides.
Journal ArticleDOI

Natriuretic Peptides—Relevance in Cardiovascular Disease

TL;DR: It appears that BNP level reflects long-term intravascular volume status rather than momentary volume, and is more stable than ANP in plasma and has a longer half-life, which may be attributable to its lesser affinity for clearance receptors.
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